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Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process. New horizons for therapeutic approaches / Marta Anna Szychlinska in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 149-156 Titre : Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process. New horizons for therapeutic approaches Type de document : texte imprimé Auteurs : Marta Anna Szychlinska, Auteur ; Rosalia Leonardi, Auteur ; Mohammed Al-Qahtani, Auteur Année de publication : 2016 Article en page(s) : p. 149-156 Langues : Anglais (eng) Français (fre) Mots-clés : Inflammation  Arthrose  Articulation  Traumatisme  Inflammation,Pro-inflammatory cytokines,Lubricin,Osteoarthritis,Joint injury Résumé : Osteoarthritis (OA) is the most common form of joint disease. This review aimed to consolidate the current evidence that implicates the inflammatory process in the attenuation of synovial lubrication and joint tissue homeostasis in OA. Moreover, with these findings, we propose some evidence for novel therapeutic strategies for preventing and/or treating this complex disorder. The studies reviewed support that inflammatory mediators participate in the onset and progression of OA after joint injury. The flow of pro-inflammatory cytokines following an acute injury seems to be directly associated with altered lubricating ability in the joint tissue. The latter is associated with reduced level of lubricin, one of the major joint lubricants. Future research should focus on the development of new therapies that attenuate the inflammatory process and restore lubricin synthesis and function. This approach could support joint tribology and synovial lubrication leading to improved joint function and pain relief. Permalink : ./index.php?lvl=notice_display&id=45204 [article] Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process. New horizons for therapeutic approaches [texte imprimé] / Marta Anna Szychlinska, Auteur ; Rosalia Leonardi, Auteur ; Mohammed Al-Qahtani, Auteur . - 2016 . - p. 149-156. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 149-156 Mots-clés : Inflammation  Arthrose  Articulation  Traumatisme  Inflammation,Pro-inflammatory cytokines,Lubricin,Osteoarthritis,Joint injury Résumé : Osteoarthritis (OA) is the most common form of joint disease. This review aimed to consolidate the current evidence that implicates the inflammatory process in the attenuation of synovial lubrication and joint tissue homeostasis in OA. Moreover, with these findings, we propose some evidence for novel therapeutic strategies for preventing and/or treating this complex disorder. The studies reviewed support that inflammatory mediators participate in the onset and progression of OA after joint injury. The flow of pro-inflammatory cytokines following an acute injury seems to be directly associated with altered lubricating ability in the joint tissue. The latter is associated with reduced level of lubricin, one of the major joint lubricants. Future research should focus on the development of new therapies that attenuate the inflammatory process and restore lubricin synthesis and function. This approach could support joint tribology and synovial lubrication leading to improved joint function and pain relief. Permalink : ./index.php?lvl=notice_display&id=45204

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Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments / Claire Vinatier in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 139-144 Titre : Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments Type de document : texte imprimé Auteurs : Claire Vinatier, Auteur ; Jérôme Guicheux, Auteur Année de publication : 2016 Article en page(s) : p. 139-144 Langues : Anglais (eng) Français (fre) Mots-clés : Tissu  Arthrose  Cellule  Biomatériau  Cartilage tissue engineering,Osteoarthritis,Stem cells,Biomaterials Résumé : Articular cartilage is a non-vascularized and poorly cellularized connective tissue that is frequently damaged as a result of trauma and degenerative joint diseases such as osteoarthrtis. Because of the absence of vascularization, articular cartilage has low capacity for spontaneous repair. Today, and despite a large number of preclinical data, no therapy capable of restoring the healthy structure and function of damaged articular cartilage is clinically available. Tissue-engineering strategies involving the combination of cells, scaffolding biomaterials and bioactive agents have been of interest notably for the repair of damaged articular cartilage. During the last 30 years, cartilage tissue engineering has evolved from the treatment of focal lesions of articular cartilage to the development of strategies targeting the osteoarthritis process. In this review, we focus on the different aspects of tissue engineering applied to cartilage engineering. We first discuss cells, biomaterials and biological or environmental factors instrumental to the development of cartilage tissue engineering, then review the potential development of cartilage engineering strategies targeting new emerging pathogenic mechanisms of osteoarthritis. Permalink : ./index.php?lvl=notice_display&id=45207 [article] Cartilage tissue engineering: From biomaterials and stem cells to osteoarthritis treatments [texte imprimé] / Claire Vinatier, Auteur ; Jérôme Guicheux, Auteur . - 2016 . - p. 139-144. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 139-144 Mots-clés : Tissu  Arthrose  Cellule  Biomatériau  Cartilage tissue engineering,Osteoarthritis,Stem cells,Biomaterials Résumé : Articular cartilage is a non-vascularized and poorly cellularized connective tissue that is frequently damaged as a result of trauma and degenerative joint diseases such as osteoarthrtis. Because of the absence of vascularization, articular cartilage has low capacity for spontaneous repair. Today, and despite a large number of preclinical data, no therapy capable of restoring the healthy structure and function of damaged articular cartilage is clinically available. Tissue-engineering strategies involving the combination of cells, scaffolding biomaterials and bioactive agents have been of interest notably for the repair of damaged articular cartilage. During the last 30 years, cartilage tissue engineering has evolved from the treatment of focal lesions of articular cartilage to the development of strategies targeting the osteoarthritis process. In this review, we focus on the different aspects of tissue engineering applied to cartilage engineering. We first discuss cells, biomaterials and biological or environmental factors instrumental to the development of cartilage tissue engineering, then review the potential development of cartilage engineering strategies targeting new emerging pathogenic mechanisms of osteoarthritis. Permalink : ./index.php?lvl=notice_display&id=45207

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Educating patients about the benefits of physical activity and exercise for their hip and knee osteoarthritis. Systematic literature review / Chloé Gay in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 174- 183 Titre : Educating patients about the benefits of physical activity and exercise for their hip and knee osteoarthritis. Systematic literature review Type de document : texte imprimé Auteurs : Chloé Gay, Auteur ; Aurore Chabaud, Auteur ; E. Guilley, Auteur Année de publication : 2016 Article en page(s) : p. 174- 183 Langues : Anglais (eng) Français (fre) Mots-clés : Genou  Hanche  Arthrose  Activité physique  Knee,Hip and osteoathritis,Self-care,Self-management,Self-efficacy and physical activity,Exercise Résumé : Objectives: Highlight the role of patient education about physical activity and exercise in the treatment of hip and knee osteoarthritis (OA). Methods: Systematic literature review from the Cochrane Library, PubMed and Wiley Online Library databases. A total of 125 items were identified, including 11 recommendations from learned societies interested in OA and 45 randomized controlled trials addressing treatment education and activity/exercise for the treatment of hip and knee osteoarthritis. Results: In the end, 13 randomized controlled trials and 8 recommendations were reviewed (1b level of evidence). Based on the analysis, it was clear that education, exercise and weight loss are the pillars of non-pharmacological treatments. These treatments have proven to be effective but require changes in patient behaviour that are difficult to obtain. Exercise and weight loss improve function and reduce pain. Education potentiates compliance to exercise and weight loss programs, thereby improving their long-term benefits. Cost efficiency studies have found a reduction in medical visits and healthcare costs after 12 months because of self-management programs. Conclusion: Among non-surgical treatment options for hip and knee osteoarthritis, the most recent guidelines focus on non-pharmacological treatment. Self-management for general physical activity and exercise has a critical role. Programs must be personalized and adjusted to the patient's phenotype. This development should help every healthcare professional adapt the care they propose to each patient. Registration number for the systematic review: CRD42015032346. Permalink : ./index.php?lvl=notice_display&id=45208 [article] Educating patients about the benefits of physical activity and exercise for their hip and knee osteoarthritis. Systematic literature review [texte imprimé] / Chloé Gay, Auteur ; Aurore Chabaud, Auteur ; E. Guilley, Auteur . - 2016 . - p. 174- 183. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 174- 183 Mots-clés : Genou  Hanche  Arthrose  Activité physique  Knee,Hip and osteoathritis,Self-care,Self-management,Self-efficacy and physical activity,Exercise Résumé : Objectives: Highlight the role of patient education about physical activity and exercise in the treatment of hip and knee osteoarthritis (OA). Methods: Systematic literature review from the Cochrane Library, PubMed and Wiley Online Library databases. A total of 125 items were identified, including 11 recommendations from learned societies interested in OA and 45 randomized controlled trials addressing treatment education and activity/exercise for the treatment of hip and knee osteoarthritis. Results: In the end, 13 randomized controlled trials and 8 recommendations were reviewed (1b level of evidence). Based on the analysis, it was clear that education, exercise and weight loss are the pillars of non-pharmacological treatments. These treatments have proven to be effective but require changes in patient behaviour that are difficult to obtain. Exercise and weight loss improve function and reduce pain. Education potentiates compliance to exercise and weight loss programs, thereby improving their long-term benefits. Cost efficiency studies have found a reduction in medical visits and healthcare costs after 12 months because of self-management programs. Conclusion: Among non-surgical treatment options for hip and knee osteoarthritis, the most recent guidelines focus on non-pharmacological treatment. Self-management for general physical activity and exercise has a critical role. Programs must be personalized and adjusted to the patient's phenotype. This development should help every healthcare professional adapt the care they propose to each patient. Registration number for the systematic review: CRD42015032346. Permalink : ./index.php?lvl=notice_display&id=45208

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Evidence and recommendations for use of intra-articular injections for knee osteoarthritis / Christelle Nguyen in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 184-189 Titre : Evidence and recommendations for use of intra-articular injections for knee osteoarthritis Type de document : texte imprimé Auteurs : Christelle Nguyen, Auteur ; Marie-Martine Lefèvre-Colau, Auteur ; Serge Poiraudeau, Auteur Année de publication : 2016 Article en page(s) : p. 184-189 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Injection  Articulation  Norme soins  Osteoarthritis,Intra-articular injections,Corticosteroids,Hyaluronic acid,Platelet-rich plasma,Botulinum toxin A,Evidence-based medicine Résumé : Pharmacological treatments are widely recommended in international guidelines for management of osteoarthritis (OA). However, the use of intra-articular (IA) therapies of diverse active drugs remains controversial. We critically reviewed studies of the efficacy and safety of IA injections of corticosteroids (CS), hyaluronic acid (HA), platelet-rich plasma (PRP), and botulinum toxin A (BTA) and evidence-based international recommendations for their use in treating knee OA. The process of article selection was unsystematic. Articles were selected on the basis of authors’ expertise, self-knowledge, and reflective practice. Only studies assessing knee OA were included. IA CS and HA injections were conditionally to fully recommended for treating knee OA. No recommendations have been formulated for IA PRP or BTA. The evidence remains inconsistent and controversial for the use of IA therapies for knee OA. The characteristics of and selection criteria for the OA population that would likely benefit from these therapies need to be identified. Accurately phenotyping and selecting patients is mandatory in future randomized controlled trials. Therefore, efficacy and safety meta-analyses should be performed, as should qualitative and sensitivity analyses of published trial results. Permalink : ./index.php?lvl=notice_display&id=45209 [article] Evidence and recommendations for use of intra-articular injections for knee osteoarthritis [texte imprimé] / Christelle Nguyen, Auteur ; Marie-Martine Lefèvre-Colau, Auteur ; Serge Poiraudeau, Auteur . - 2016 . - p. 184-189. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 184-189 Mots-clés : Arthrose  Injection  Articulation  Norme soins  Osteoarthritis,Intra-articular injections,Corticosteroids,Hyaluronic acid,Platelet-rich plasma,Botulinum toxin A,Evidence-based medicine Résumé : Pharmacological treatments are widely recommended in international guidelines for management of osteoarthritis (OA). However, the use of intra-articular (IA) therapies of diverse active drugs remains controversial. We critically reviewed studies of the efficacy and safety of IA injections of corticosteroids (CS), hyaluronic acid (HA), platelet-rich plasma (PRP), and botulinum toxin A (BTA) and evidence-based international recommendations for their use in treating knee OA. The process of article selection was unsystematic. Articles were selected on the basis of authors’ expertise, self-knowledge, and reflective practice. Only studies assessing knee OA were included. IA CS and HA injections were conditionally to fully recommended for treating knee OA. No recommendations have been formulated for IA PRP or BTA. The evidence remains inconsistent and controversial for the use of IA therapies for knee OA. The characteristics of and selection criteria for the OA population that would likely benefit from these therapies need to be identified. Accurately phenotyping and selecting patients is mandatory in future randomized controlled trials. Therefore, efficacy and safety meta-analyses should be performed, as should qualitative and sensitivity analyses of published trial results. Permalink : ./index.php?lvl=notice_display&id=45209

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Imaging for osteoarthritis / Daichi Hayashi in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 161-169 Titre : Imaging for osteoarthritis Type de document : texte imprimé Auteurs : Daichi Hayashi, Auteur ; Frank Roemer, Auteur ; Ali Guermazi, Auteur Année de publication : 2016 Article en page(s) : p. 161-169 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Imagerie médicale  Imagerie résonance magnétique  Scanner  Radiographie  Osteoarthritis,Imaging,Radiography,MR imaging,Ultrasound,CT,PET Résumé : Osteoarthritis (OA) is a widely prevalent disease worldwide and, with an increasing ageing society, is a challenge for the field of physical and rehabilitation medicine. Technologic advances and implementation of sophisticated post-processing instruments and analytic strategies have resulted in imaging playing a more and more important role in understanding the disease process of OA. Radiography is still the most commonly used imaging modality for establishing an imaging-based diagnosis of OA. The need for an effective non-surgical OA treatment is highly desired, but despite on-going research efforts no disease-modifying OA drugs have been discovered or approved to date. MR imaging-based studies have revealed some of the limitations of radiography. The ability of MR to image all relevant joint tissues within the knee and to visualize cartilage morphology and composition has resulted in MRI playing a key role in understanding the natural history of the disease and in the search for new therapies. Our review will focus on the roles and limitations of radiography and MRI with particular attention to knee OA. The use of other modalities (e.g. ultrasound, nuclear medicine, computed tomography (CT), and CT/MR arthrography) in clinical practice and OA research will also be briefly described. Ultrasound may be useful to evaluate synovial pathology in osteoarthritis, particularly in the hand. Permalink : ./index.php?lvl=notice_display&id=45211 [article] Imaging for osteoarthritis [texte imprimé] / Daichi Hayashi, Auteur ; Frank Roemer, Auteur ; Ali Guermazi, Auteur . - 2016 . - p. 161-169. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 161-169 Mots-clés : Arthrose  Imagerie médicale  Imagerie résonance magnétique  Scanner  Radiographie  Osteoarthritis,Imaging,Radiography,MR imaging,Ultrasound,CT,PET Résumé : Osteoarthritis (OA) is a widely prevalent disease worldwide and, with an increasing ageing society, is a challenge for the field of physical and rehabilitation medicine. Technologic advances and implementation of sophisticated post-processing instruments and analytic strategies have resulted in imaging playing a more and more important role in understanding the disease process of OA. Radiography is still the most commonly used imaging modality for establishing an imaging-based diagnosis of OA. The need for an effective non-surgical OA treatment is highly desired, but despite on-going research efforts no disease-modifying OA drugs have been discovered or approved to date. MR imaging-based studies have revealed some of the limitations of radiography. The ability of MR to image all relevant joint tissues within the knee and to visualize cartilage morphology and composition has resulted in MRI playing a key role in understanding the natural history of the disease and in the search for new therapies. Our review will focus on the roles and limitations of radiography and MRI with particular attention to knee OA. The use of other modalities (e.g. ultrasound, nuclear medicine, computed tomography (CT), and CT/MR arthrography) in clinical practice and OA research will also be briefly described. Ultrasound may be useful to evaluate synovial pathology in osteoarthritis, particularly in the hand. Permalink : ./index.php?lvl=notice_display&id=45211

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Is physical activity, practiced as recommended for health benefit, a risk factor for osteoarthritis? / Marie-Martine Lefèvre-Colau in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 196-206 Titre : Is physical activity, practiced as recommended for health benefit, a risk factor for osteoarthritis? Type de document : texte imprimé Auteurs : Marie-Martine Lefèvre-Colau, Auteur ; Christelle Nguyen, Auteur ; Rebecca Haddad, Auteur Année de publication : 2016 Article en page(s) : p. 196-206 Langues : Anglais (eng) Français (fre) Mots-clés : Activité physique  Sport  Arthrose  Traumatisme  Articulation  Impact  Sport intensif  Physical activity,Exercises,Sports,Osteoarthritis,Risk factor,Injuries,Joint injuries,Impact,Elite athletes Résumé : In this critical narrative review, we examine the role of physical activity (PA), recreational and elite sports in the development of knee/hip osteoarthritis (OA), taking into account the role of injury in this relationship. The process of article selection was unsystematic. Articles were selected on the basis of the authors’ expertise, self-knowledge, and reflective practice. In the general adult population, self-reported diagnosis of knee/hip OA was not associated with low, moderate or high levels of PA. For studies using radiographic knee/hip OA as a primary outcome, the incidence of asymptomatic radiographic OA was higher for subjects with the highest quartile of usual PA than the least active subjects. The risk of incident radiographic knee/hip OA features was increased for subjects with a history of regular sports participation (for osteophyte formation but not joint space narrowing). This risk depended on the type of sport (team and power sports but not endurance and running), and certain conditions (high level of practice) were closely related to the risk of injury. The prevalence of radiographic OA was significantly higher, especially the presence of osteophytes, in former elite athletes than controls. The risk of OA was higher with participation in mixed sports, especially soccer or power sports, than endurance sport. However, the prevalence of clinical OA between former elite athletes and controls was similar, with less hip/knee disability in former athletes. Moderate daily recreational or sport activities, whatever the type of sport, are not a consistent risk factor for clinical or radiographic knee/hip OA. Risk of injury in different sports may be the key factor to understanding the risk of OA related to sport. Permalink : ./index.php?lvl=notice_display&id=45212 [article] Is physical activity, practiced as recommended for health benefit, a risk factor for osteoarthritis? [texte imprimé] / Marie-Martine Lefèvre-Colau, Auteur ; Christelle Nguyen, Auteur ; Rebecca Haddad, Auteur . - 2016 . - p. 196-206. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 196-206 Mots-clés : Activité physique  Sport  Arthrose  Traumatisme  Articulation  Impact  Sport intensif  Physical activity,Exercises,Sports,Osteoarthritis,Risk factor,Injuries,Joint injuries,Impact,Elite athletes Résumé : In this critical narrative review, we examine the role of physical activity (PA), recreational and elite sports in the development of knee/hip osteoarthritis (OA), taking into account the role of injury in this relationship. The process of article selection was unsystematic. Articles were selected on the basis of the authors’ expertise, self-knowledge, and reflective practice. In the general adult population, self-reported diagnosis of knee/hip OA was not associated with low, moderate or high levels of PA. For studies using radiographic knee/hip OA as a primary outcome, the incidence of asymptomatic radiographic OA was higher for subjects with the highest quartile of usual PA than the least active subjects. The risk of incident radiographic knee/hip OA features was increased for subjects with a history of regular sports participation (for osteophyte formation but not joint space narrowing). This risk depended on the type of sport (team and power sports but not endurance and running), and certain conditions (high level of practice) were closely related to the risk of injury. The prevalence of radiographic OA was significantly higher, especially the presence of osteophytes, in former elite athletes than controls. The risk of OA was higher with participation in mixed sports, especially soccer or power sports, than endurance sport. However, the prevalence of clinical OA between former elite athletes and controls was similar, with less hip/knee disability in former athletes. Moderate daily recreational or sport activities, whatever the type of sport, are not a consistent risk factor for clinical or radiographic knee/hip OA. Risk of injury in different sports may be the key factor to understanding the risk of OA related to sport. Permalink : ./index.php?lvl=notice_display&id=45212

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Isokinetic muscle strengthening for knee osteoarthritis: A systematic review of randomized controlled trials with meta-analysis / Emmanuel Coudeyre in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 207-215 Titre : Isokinetic muscle strengthening for knee osteoarthritis: A systematic review of randomized controlled trials with meta-analysis Type de document : texte imprimé Auteurs : Emmanuel Coudeyre, Auteur ; Anne-Gaëlle Jegu, Auteur ; Mathias Giustanini, Auteur Année de publication : 2016 Article en page(s) : p. 207-215 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Genou  Muscle  Activité physique  Knee osteoarthritis,Isokinetic,Muscle,Exercise Résumé : Objective: To assess the level of scientific evidence and the place in the rehabilitation framework of isokinetic muscle strengthening (IMS) for knee osteoarthritis (OA). Methods: A systematic review of the English literature in MEDLINE via PubMed, the Cochrane Library, and PEDro databases for only randomized comparative trials. Data that were sufficiently homogeneous underwent comprehensive meta-analysis. Methodological assessment was done by using the CLEAR scale for non-pharmacologic trials. Results: We identified articles for 9 trials (696 patients). All trials were of low to moderate quality. Tolerance of IMS was considered good. Improvement in muscle strength was better with an IMS program than no treatment or an isometric exercise but did not differ with an aerobic program. We found an important effect for pain (standardized mean difference 1.218 [95% CI 0.899–1.54], P <0.001) and functional Lequesne index (1.61 [0.40–2.81], P =0.009) and a moderate effect for the Western Ontario and McMaster Universities Osteoarthritis Index subscore C for disability (0.58 [0.04–1.11], P =0.03). Conclusions: IMS is an effective way to propose dynamic muscle strengthening for knee OA rehabilitation and has a significant effect on pain and disability. Because of the weak methodology and the great heterogeneity of studies, particularly in IMS protocol and outcome measures, insufficient data are available to provide guidelines about efficacy and strategy. Future clinical trials are needed, but more attention should be paid to the methods of such studies to clarify the role of IMS in the therapeutic armamentarium of knee OA. Permalink : ./index.php?lvl=notice_display&id=45213 [article] Isokinetic muscle strengthening for knee osteoarthritis: A systematic review of randomized controlled trials with meta-analysis [texte imprimé] / Emmanuel Coudeyre, Auteur ; Anne-Gaëlle Jegu, Auteur ; Mathias Giustanini, Auteur . - 2016 . - p. 207-215. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 207-215 Mots-clés : Arthrose  Genou  Muscle  Activité physique  Knee osteoarthritis,Isokinetic,Muscle,Exercise Résumé : Objective: To assess the level of scientific evidence and the place in the rehabilitation framework of isokinetic muscle strengthening (IMS) for knee osteoarthritis (OA). Methods: A systematic review of the English literature in MEDLINE via PubMed, the Cochrane Library, and PEDro databases for only randomized comparative trials. Data that were sufficiently homogeneous underwent comprehensive meta-analysis. Methodological assessment was done by using the CLEAR scale for non-pharmacologic trials. Results: We identified articles for 9 trials (696 patients). All trials were of low to moderate quality. Tolerance of IMS was considered good. Improvement in muscle strength was better with an IMS program than no treatment or an isometric exercise but did not differ with an aerobic program. We found an important effect for pain (standardized mean difference 1.218 [95% CI 0.899–1.54], P <0.001) and functional Lequesne index (1.61 [0.40–2.81], P =0.009) and a moderate effect for the Western Ontario and McMaster Universities Osteoarthritis Index subscore C for disability (0.58 [0.04–1.11], P =0.03). Conclusions: IMS is an effective way to propose dynamic muscle strengthening for knee OA rehabilitation and has a significant effect on pain and disability. Because of the weak methodology and the great heterogeneity of studies, particularly in IMS protocol and outcome measures, insufficient data are available to provide guidelines about efficacy and strategy. Future clinical trials are needed, but more attention should be paid to the methods of such studies to clarify the role of IMS in the therapeutic armamentarium of knee OA. Permalink : ./index.php?lvl=notice_display&id=45213

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Osteoarthritis biomarkers derived from cartilage extracellular matrix: Current status and future perspectives / Yves Henrotin in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 145-148 Titre : Osteoarthritis biomarkers derived from cartilage extracellular matrix: Current status and future perspectives Type de document : texte imprimé Auteurs : Yves Henrotin, Auteur ; Christelle Sanchez, Auteur ; Anne-Christine Bay-Jensen, Auteur Année de publication : 2016 Article en page(s) : p. 145-148 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Osteoarthritis,Biomarkers,Cartilage,Extracellular matrix Résumé : Specific soluble biomarkers can be powerful tools for the diagnosis, prognosis and personalized management of osteoarthritis (OA). Biomarkers are potential indicators of the effect of a drug on cartilage metabolism and provide crucial information about the mechanisms of drug action. In this review, we address key questions concerning the use of biomarkers in OA management: Why do we need soluble biomarkers? What are the most widely investigated biomarkers derived from cartilage extracellular matrix? What are the most common pitfalls in interpreting soluble biomarker measurements? What are the perspectives and future research directions in this field? We review current evidence to propose that cartilage-derived soluble biomarkers are complementary “drug development tools” that can be applied during drug development from preclinical research to clinical evaluation. In the future, such biomarkers could be surrogate markers of clinical and/or imaging outcomes. Successful standardization and implementation of automated biomarker assays will facilitate their use in companion diagnostics in the context of personalized medicine for enhanced management of OA. Permalink : ./index.php?lvl=notice_display&id=45214 [article] Osteoarthritis biomarkers derived from cartilage extracellular matrix: Current status and future perspectives [texte imprimé] / Yves Henrotin, Auteur ; Christelle Sanchez, Auteur ; Anne-Christine Bay-Jensen, Auteur . - 2016 . - p. 145-148. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 145-148 Mots-clés : Arthrose  Osteoarthritis,Biomarkers,Cartilage,Extracellular matrix Résumé : Specific soluble biomarkers can be powerful tools for the diagnosis, prognosis and personalized management of osteoarthritis (OA). Biomarkers are potential indicators of the effect of a drug on cartilage metabolism and provide crucial information about the mechanisms of drug action. In this review, we address key questions concerning the use of biomarkers in OA management: Why do we need soluble biomarkers? What are the most widely investigated biomarkers derived from cartilage extracellular matrix? What are the most common pitfalls in interpreting soluble biomarker measurements? What are the perspectives and future research directions in this field? We review current evidence to propose that cartilage-derived soluble biomarkers are complementary “drug development tools” that can be applied during drug development from preclinical research to clinical evaluation. In the future, such biomarkers could be surrogate markers of clinical and/or imaging outcomes. Successful standardization and implementation of automated biomarker assays will facilitate their use in companion diagnostics in the context of personalized medicine for enhanced management of OA. Permalink : ./index.php?lvl=notice_display&id=45214

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Osteoarthritis guidelines: Barriers to implementation and solutions / Sarah Ferreira de Meneses in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 170-173 Titre : Osteoarthritis guidelines: Barriers to implementation and solutions Type de document : texte imprimé Auteurs : Sarah Ferreira de Meneses, Auteur ; François Rannou, Auteur ; David J. Hunter, Auteur Année de publication : 2016 Article en page(s) : p. 170-173 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Norme soins  Osteoarthritis,Clinical practice guidelines,Implementation Résumé : Osteoarthritis (OA) is a leading cause of disability worldwide. Clinical practice guidelines (CPGs) have been developed to facilitate improved OA management. Scientific communities worldwide have proposed CPGs for OA treatment. Despite the number of highly prominent guidelines available and their remarkable consistency, their uptake has been suboptimal. Possibly because of the multitude of barriers related to the implementation of CPGs. For example, different guidelines show contradictions, some lack evidence, and they lack a hierarchy or tools to facilitate their translation and application. Also, the guidelines do not acknowledge the effect of comorbidities on choosing the treatments. Finally, poor integration of multidisciplinary services within and across healthcare settings is a major barrier to the effective implementation of management guidelines. Here we describe the main problems related to the OA guidelines and some solutions so as to offer some guidance on the elaboration of future CPGs and their implementation in primary care. Permalink : ./index.php?lvl=notice_display&id=45215 [article] Osteoarthritis guidelines: Barriers to implementation and solutions [texte imprimé] / Sarah Ferreira de Meneses, Auteur ; François Rannou, Auteur ; David J. Hunter, Auteur . - 2016 . - p. 170-173. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 170-173 Mots-clés : Arthrose  Norme soins  Osteoarthritis,Clinical practice guidelines,Implementation Résumé : Osteoarthritis (OA) is a leading cause of disability worldwide. Clinical practice guidelines (CPGs) have been developed to facilitate improved OA management. Scientific communities worldwide have proposed CPGs for OA treatment. Despite the number of highly prominent guidelines available and their remarkable consistency, their uptake has been suboptimal. Possibly because of the multitude of barriers related to the implementation of CPGs. For example, different guidelines show contradictions, some lack evidence, and they lack a hierarchy or tools to facilitate their translation and application. Also, the guidelines do not acknowledge the effect of comorbidities on choosing the treatments. Finally, poor integration of multidisciplinary services within and across healthcare settings is a major barrier to the effective implementation of management guidelines. Here we describe the main problems related to the OA guidelines and some solutions so as to offer some guidance on the elaboration of future CPGs and their implementation in primary care. Permalink : ./index.php?lvl=notice_display&id=45215

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Osteoarthritis in physical medicine and rehabilitation / Emmanuel Coudeyre in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 133 Titre : Osteoarthritis in physical medicine and rehabilitation Type de document : texte imprimé Auteurs : Emmanuel Coudeyre, Auteur ; Virginia Byers Kraus, Auteur ; François Rannou, Auteur Année de publication : 2016 Article en page(s) : p. 133 Note générale : Editorial Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Rééducation fonctionnelle Résumé : The increasing prevalence of osteoarthritis (OA), due mainly to ageing and lifestyle risk factors (obesity, sedentarity and sport injuries) heightens the importance of addressing OA rehabilitation in the practice of physical medicine and rehabilitation (PRM). Non-pharmacological interventions are now the first-line OA therapies worldwide. Thus, the number of patients referred to PMR physicians is expected to increase in the future. PMR physicians have to play a pivotal role in the management of OA especially with respect to biomechanical and exercise interventions and self-care enhancement. Permalink : ./index.php?lvl=notice_display&id=45216 [article] Osteoarthritis in physical medicine and rehabilitation [texte imprimé] / Emmanuel Coudeyre, Auteur ; Virginia Byers Kraus, Auteur ; François Rannou, Auteur . - 2016 . - p. 133. Editorial Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 133 Mots-clés : Arthrose  Rééducation fonctionnelle Résumé : The increasing prevalence of osteoarthritis (OA), due mainly to ageing and lifestyle risk factors (obesity, sedentarity and sport injuries) heightens the importance of addressing OA rehabilitation in the practice of physical medicine and rehabilitation (PRM). Non-pharmacological interventions are now the first-line OA therapies worldwide. Thus, the number of patients referred to PMR physicians is expected to increase in the future. PMR physicians have to play a pivotal role in the management of OA especially with respect to biomechanical and exercise interventions and self-care enhancement. Permalink : ./index.php?lvl=notice_display&id=45216

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Osteoarthritis, obesity and type 2 diabetes: The weight of waist circumference / Martine Duclos in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 157-160 Titre : Osteoarthritis, obesity and type 2 diabetes: The weight of waist circumference Type de document : texte imprimé Auteurs : Martine Duclos, Auteur Année de publication : 2016 Article en page(s) : p. 157-160 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Diabète  Obésité  Activité physique  Obesity,Type 2 diabetes,Abdominal obesity,Osteo-arthrosis,Adipokines,Physical activity Résumé : Background: Obesity and type 2 diabetes (T2D) significantly increase the risk of developing an arthritic condition. Methods: We performed a review of literature on the pathophysiological mechanisms that underpin the relationships between obesity, T2D and osteoarthritis (OA). Results: The pathophysiology of the link between obesity and OA is related to both the direct effect of excess mechanical loads being placed on the cartilage and to an adipose tissue effect. Adipocytes produce and release adipokines (e.g. leptin). They are also the seat of a local inflammatory reaction when the adipose tissue is ectopic (visceral vs. subcutaneous adipose tissue), and then systemic effects that add even more to a micro-inflammatory mechanism. In diabetics, insulin resistance can add to these mechanisms, which can damage cartilage, bone and synovial tissue. These all act together to reduce mobility in obese subjects and contribute to a vicious cycle centered on OA, especially when the obesity is predominantly abdominal and/or associated with T2D. Discussion: Prevention of obesity-related OA must be the focus in high-risk subjects, such as those who are obese with metabolic syndrome>“metabolically healthy” obese, have T2D, and normal weight subjects with abdominal obesity (defined as waist circumference>102cm for men and 88cm for women). The primary component of this prevention effort is weight loss combined with a balanced diet and regular physical activity. Permalink : ./index.php?lvl=notice_display&id=45217 [article] Osteoarthritis, obesity and type 2 diabetes: The weight of waist circumference [texte imprimé] / Martine Duclos, Auteur . - 2016 . - p. 157-160. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 157-160 Mots-clés : Arthrose  Diabète  Obésité  Activité physique  Obesity,Type 2 diabetes,Abdominal obesity,Osteo-arthrosis,Adipokines,Physical activity Résumé : Background: Obesity and type 2 diabetes (T2D) significantly increase the risk of developing an arthritic condition. Methods: We performed a review of literature on the pathophysiological mechanisms that underpin the relationships between obesity, T2D and osteoarthritis (OA). Results: The pathophysiology of the link between obesity and OA is related to both the direct effect of excess mechanical loads being placed on the cartilage and to an adipose tissue effect. Adipocytes produce and release adipokines (e.g. leptin). They are also the seat of a local inflammatory reaction when the adipose tissue is ectopic (visceral vs. subcutaneous adipose tissue), and then systemic effects that add even more to a micro-inflammatory mechanism. In diabetics, insulin resistance can add to these mechanisms, which can damage cartilage, bone and synovial tissue. These all act together to reduce mobility in obese subjects and contribute to a vicious cycle centered on OA, especially when the obesity is predominantly abdominal and/or associated with T2D. Discussion: Prevention of obesity-related OA must be the focus in high-risk subjects, such as those who are obese with metabolic syndrome>“metabolically healthy” obese, have T2D, and normal weight subjects with abdominal obesity (defined as waist circumference>102cm for men and 88cm for women). The primary component of this prevention effort is weight loss combined with a balanced diet and regular physical activity. Permalink : ./index.php?lvl=notice_display&id=45217

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Rehabilitation (exercise and strength training) and osteoarthritis: A critical narrative review / Christelle Nguyen in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 190-195 Titre : Rehabilitation (exercise and strength training) and osteoarthritis: A critical narrative review Type de document : texte imprimé Auteurs : Christelle Nguyen, Auteur ; Marie-Martine Lefèvre-Colau, Auteur ; Serge Poiraudeau, Auteur Année de publication : 2016 Article en page(s) : p. 190-195 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Rééducation fonctionnelle  Médecine fondée sur les preuves  Activité physique  Osteoarthritis,Rehabilitation,Exercise,Strength training,Evidence-based medicine Résumé : Rehabilitation is widely recommended in national and international guidelines for managing osteoarthritis (OA) in primary care settings. According to the 2014 OA Research Society International (OARSI) recommendations, rehabilitation is even considered the core treatment of OA and is recommended for all patients. Rehabilitation for OA widely includes land- and water-based exercise, strength training, weight management, self-management and education, biomechanical interventions, and physically active lifestyle. We performed a critical narrative review of the efficacy and safety of rehabilitation for managing OA and discuss evidence-based international recommendations. The process of article selection was unsystematic. Articles were selected based on authors’ expertise, self-knowledge, and reflective practice. For the purpose of the review, we focused on land- and water-based exercise and strength training for knee, hip and hand OA. Other aspects of rehabilitation in OA are treated elsewhere in this special issue. Exercise therapy is widely recommended for managing knee, hip and hand OA. However, the level of evidence varies according to OA location. Overall, consistent evidence suggests that exercise therapy and specific strengthening exercise or strength training for the lower limb reduce pain and improve physical function in knee OA. Evidence for other OA sites are less consistent. Therefore, because of the lack of specific studies, recommendations for hip and hand OA are mainly derived from studies of knee OA. In addition, no recommendations have been established regarding the exercise regimen. The efficacy and safety of exercise therapy and strength training need to be further evaluated in randomized controlled trials of patients with hip and hand OA. The optimal delivery of exercise programs also has to be more clearly defined. Permalink : ./index.php?lvl=notice_display&id=45221 [article] Rehabilitation (exercise and strength training) and osteoarthritis: A critical narrative review [texte imprimé] / Christelle Nguyen, Auteur ; Marie-Martine Lefèvre-Colau, Auteur ; Serge Poiraudeau, Auteur . - 2016 . - p. 190-195. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 190-195 Mots-clés : Arthrose  Rééducation fonctionnelle  Médecine fondée sur les preuves  Activité physique  Osteoarthritis,Rehabilitation,Exercise,Strength training,Evidence-based medicine Résumé : Rehabilitation is widely recommended in national and international guidelines for managing osteoarthritis (OA) in primary care settings. According to the 2014 OA Research Society International (OARSI) recommendations, rehabilitation is even considered the core treatment of OA and is recommended for all patients. Rehabilitation for OA widely includes land- and water-based exercise, strength training, weight management, self-management and education, biomechanical interventions, and physically active lifestyle. We performed a critical narrative review of the efficacy and safety of rehabilitation for managing OA and discuss evidence-based international recommendations. The process of article selection was unsystematic. Articles were selected based on authors’ expertise, self-knowledge, and reflective practice. For the purpose of the review, we focused on land- and water-based exercise and strength training for knee, hip and hand OA. Other aspects of rehabilitation in OA are treated elsewhere in this special issue. Exercise therapy is widely recommended for managing knee, hip and hand OA. However, the level of evidence varies according to OA location. Overall, consistent evidence suggests that exercise therapy and specific strengthening exercise or strength training for the lower limb reduce pain and improve physical function in knee OA. Evidence for other OA sites are less consistent. Therefore, because of the lack of specific studies, recommendations for hip and hand OA are mainly derived from studies of knee OA. In addition, no recommendations have been established regarding the exercise regimen. The efficacy and safety of exercise therapy and strength training need to be further evaluated in randomized controlled trials of patients with hip and hand OA. The optimal delivery of exercise programs also has to be more clearly defined. Permalink : ./index.php?lvl=notice_display&id=45221

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Risk factors and burden of osteoarthritis / Clémence Palazzo in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 134-138 Titre : Risk factors and burden of osteoarthritis Type de document : texte imprimé Auteurs : Clémence Palazzo, Auteur ; Christelle Nguyen, Auteur ; Marie-Martine Lefèvre-Colau, Auteur Année de publication : 2016 Article en page(s) : p. 134-138 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Épidémiologie  Indicateur risque  Handicap  Epidemiology,Osteoarthritis,Risk factors,Mortality,Disability,Prevalence,Burden Résumé : Osteoarthritis (OA) is one of the most common joint disorders worldwide. Its prevalence is increasing because of the growing aging of the population in developed and developing countries as well as an increase in risk factors leading to OA, particularly obesity and a sedentary lifestyle. Risk factors of OA can be divided into person-level factors (age, gender, obesity, genetics and diet) and joint-level factors (injury, malalignment and abnormal loading of the joints) that interact in a complex manner. OA is the 11th cause of disability in the world. It is responsible for activity limitations, particularly walking, and affects participation and quality of life. Patients with OA are at greater risk of all-cause mortality, particularly for cardiovascular diseases, than the general population. This excess mortality is closely associated with disability level. Consequently, strategies to reduce burden through primary and secondary prevention programs are increasingly important. Permalink : ./index.php?lvl=notice_display&id=45222 [article] Risk factors and burden of osteoarthritis [texte imprimé] / Clémence Palazzo, Auteur ; Christelle Nguyen, Auteur ; Marie-Martine Lefèvre-Colau, Auteur . - 2016 . - p. 134-138. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 134-138 Mots-clés : Arthrose  Épidémiologie  Indicateur risque  Handicap  Epidemiology,Osteoarthritis,Risk factors,Mortality,Disability,Prevalence,Burden Résumé : Osteoarthritis (OA) is one of the most common joint disorders worldwide. Its prevalence is increasing because of the growing aging of the population in developed and developing countries as well as an increase in risk factors leading to OA, particularly obesity and a sedentary lifestyle. Risk factors of OA can be divided into person-level factors (age, gender, obesity, genetics and diet) and joint-level factors (injury, malalignment and abnormal loading of the joints) that interact in a complex manner. OA is the 11th cause of disability in the world. It is responsible for activity limitations, particularly walking, and affects participation and quality of life. Patients with OA are at greater risk of all-cause mortality, particularly for cardiovascular diseases, than the general population. This excess mortality is closely associated with disability level. Consequently, strategies to reduce burden through primary and secondary prevention programs are increasingly important. Permalink : ./index.php?lvl=notice_display&id=45222

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Spa therapy and knee osteoarthritis: A systematic review / Romain FORESTIER in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 216-226 Titre : Spa therapy and knee osteoarthritis: A systematic review Type de document : texte imprimé Auteurs : Romain FORESTIER, Auteur ; Alain Francon, Auteur ; Fatma Begüm Erol Forestier, Auteur Année de publication : 2016 Article en page(s) : p. 216-226 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Thalassothérapie  Thermalisme  Hydrothérapie  Boue thermale  Revue de littérature  Osteoarthritis,Crenobalneotherapy,Spa therapy,Hydrotherapy,Mud,Radon Résumé : Background: Osteoarthritis (OA) is a public health problem that will probably increase in the future with the aging of the population. Crenobalneotherapy is commonly used to treat OA, but evidence from previous reviews was not sufficient. This systematic review aimed to identify the best evidence for the clinical effect of crenobalneotherapy for knee OA. Methods: We systematically searched MEDLINE via PubMed, PEDRO and the Cochrane Central Register of Controlled Trials for articles published up to September 2015. Articles were included if trials were comparative, if one or more of the subgroups had knee OA with separate data, and if spa therapy or any hydrotherapy techniques involving mineral water or mineral mud was compared to any other intervention or no treatment. Statistical validity, external validity and quality of side effects assessment were evaluated by personal checklists. Risk of bias was assessed by the CLEAR NTP. Results: Treatments (hot mineral water baths, mud therapy, hot showers, and sometimes massage and supervised water exercises) delivered in spa centers across Europe and the Middle East seem to improve symptoms in knee OA. They may be effective for pain and function. There are conflicting results about the effect on quality of life and drug consumption. Conclusions: Improvements with spa therapy for knee OA appear to be clinically relevant until 3 to 6 months and sometimes 9 months. Permalink : ./index.php?lvl=notice_display&id=45223 [article] Spa therapy and knee osteoarthritis: A systematic review [texte imprimé] / Romain FORESTIER, Auteur ; Alain Francon, Auteur ; Fatma Begüm Erol Forestier, Auteur . - 2016 . - p. 216-226. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 216-226 Mots-clés : Arthrose  Thalassothérapie  Thermalisme  Hydrothérapie  Boue thermale  Revue de littérature  Osteoarthritis,Crenobalneotherapy,Spa therapy,Hydrotherapy,Mud,Radon Résumé : Background: Osteoarthritis (OA) is a public health problem that will probably increase in the future with the aging of the population. Crenobalneotherapy is commonly used to treat OA, but evidence from previous reviews was not sufficient. This systematic review aimed to identify the best evidence for the clinical effect of crenobalneotherapy for knee OA. Methods: We systematically searched MEDLINE via PubMed, PEDRO and the Cochrane Central Register of Controlled Trials for articles published up to September 2015. Articles were included if trials were comparative, if one or more of the subgroups had knee OA with separate data, and if spa therapy or any hydrotherapy techniques involving mineral water or mineral mud was compared to any other intervention or no treatment. Statistical validity, external validity and quality of side effects assessment were evaluated by personal checklists. Risk of bias was assessed by the CLEAR NTP. Results: Treatments (hot mineral water baths, mud therapy, hot showers, and sometimes massage and supervised water exercises) delivered in spa centers across Europe and the Middle East seem to improve symptoms in knee OA. They may be effective for pain and function. There are conflicting results about the effect on quality of life and drug consumption. Conclusions: Improvements with spa therapy for knee OA appear to be clinically relevant until 3 to 6 months and sometimes 9 months. Permalink : ./index.php?lvl=notice_display&id=45223

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Surgical treatments for osteoarthritis / Nicolas de l' Escalopier in Annals of physical and rehabilitation medicine, Vol. 59, n° 3 (June 2016)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 227-233 Titre : Surgical treatments for osteoarthritis Type de document : texte imprimé Auteurs : Nicolas de l' Escalopier, Auteur ; Philippe Anract, Auteur ; David Biau, Auteur Année de publication : 2016 Article en page(s) : p. 227-233 Langues : Anglais (eng) Français (fre) Mots-clés : Arthrose  Articulation  Chirurgie orthopédique  Genou  Hanche  Épaule  Osteoarthritis,Joint arthroplasty,Conservative surgery,Hip,Knee,Shoulder Résumé : There are two main surgical treatments for osteoarthritis: conservative treatments, where the damaged cartilage is left in place, and radical treatments, where the cartilage is replaced by an artificial endoprosthesis; this latter procedure is termed joint arthroplasty. These treatments are only offered to symptomatic patients. Arthrodesis is yet another surgical intervention in cases of osteoarthritis. It will sacrifice the joint's articular function and is performed on small osteoarthritic joints, such as wrists and ankles, for instance. Osteoarthritis symptoms are usually the consequence of an imbalance between the load applied to a joint and the surface available to support that load. Therefore, conservative treatments will either tend to decrease the load exerted on the joint, such as in a tibial valgus osteotomy for instance, or to improve the articular surface supporting that load. Sometimes, both can be provided at the same time; the peri-acetabular osteotomy for hip dysplasia is an example of such a procedure. Conservative treatments are usually offered to young patients in order to delay, if not avoid, the need for a joint prosthesis. They are usually performed before osteoarthritis appears or at an early stage. Joint arthroplasties have overwhelmingly excellent functional results and today's research is directed towards providing rapid recovery, very long-term stability, and the assurance of a good functionality in extreme conditions. However, complications with joint arthroplasties can be serious with little, if any, reasonable salvage solution. Therefore, these procedures are offered to patients who have failed adequate medical treatment measures. Permalink : ./index.php?lvl=notice_display&id=45224 [article] Surgical treatments for osteoarthritis [texte imprimé] / Nicolas de l' Escalopier, Auteur ; Philippe Anract, Auteur ; David Biau, Auteur . - 2016 . - p. 227-233. Langues : Anglais (eng) Français (fre) in Annals of physical and rehabilitation medicine > Vol. 59, n° 3 (June 2016) . - p. 227-233 Mots-clés : Arthrose  Articulation  Chirurgie orthopédique  Genou  Hanche  Épaule  Osteoarthritis,Joint arthroplasty,Conservative surgery,Hip,Knee,Shoulder Résumé : There are two main surgical treatments for osteoarthritis: conservative treatments, where the damaged cartilage is left in place, and radical treatments, where the cartilage is replaced by an artificial endoprosthesis; this latter procedure is termed joint arthroplasty. These treatments are only offered to symptomatic patients. Arthrodesis is yet another surgical intervention in cases of osteoarthritis. It will sacrifice the joint's articular function and is performed on small osteoarthritic joints, such as wrists and ankles, for instance. Osteoarthritis symptoms are usually the consequence of an imbalance between the load applied to a joint and the surface available to support that load. Therefore, conservative treatments will either tend to decrease the load exerted on the joint, such as in a tibial valgus osteotomy for instance, or to improve the articular surface supporting that load. Sometimes, both can be provided at the same time; the peri-acetabular osteotomy for hip dysplasia is an example of such a procedure. Conservative treatments are usually offered to young patients in order to delay, if not avoid, the need for a joint prosthesis. They are usually performed before osteoarthritis appears or at an early stage. Joint arthroplasties have overwhelmingly excellent functional results and today's research is directed towards providing rapid recovery, very long-term stability, and the assurance of a good functionality in extreme conditions. However, complications with joint arthroplasties can be serious with little, if any, reasonable salvage solution. Therefore, these procedures are offered to patients who have failed adequate medical treatment measures. Permalink : ./index.php?lvl=notice_display&id=45224

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