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Effect of a high-intensity interval training on serum microRNA levels in women with breast cancer undergoing hormone therapy. A single-blind randomized trial / Shaban Alizadeh in Annals of physical and rehabilitation medicine, Vol. 62, n°5 (Septembre 2019)
[article]
Titre : Effect of a high-intensity interval training on serum microRNA levels in women with breast cancer undergoing hormone therapy. A single-blind randomized trial Type de document : texte imprimé Auteurs : Shaban Alizadeh ; Amin Isanejad ; Sanambar Sadighi ; Solmaz Khalighfard ; Ali Mohammad Alizadeh Année de publication : 2019 Article en page(s) : p. 329-335 Note générale : doi.org/10.1016/j.rehab.2019.07.001 Langues : Anglais (eng) Mots-clés : microRNAs Breast cancer Hormone therapy Training Résumé : Background
The role of microRNAs (miRs) in hormone therapy (HT) is of keen interest in developing biomarkers and treatments for individuals with breast cancer. Although miRs are often moderate regulators under homeostatic conditions, their function is changed more in response to physical activity.
Objective
This single-blind randomized trial aimed to explore the effect of high-intensity interval training (HIIT) on serum levels of miRs in individuals with early-stage breast cancer undergoing HT.
Methods
Hormone receptor-positive women with breast cancer and healthy women were randomly assigned to a healthy control group (n = 15), healthy group with HIIT (n = 15), breast cancer group with HT (HT, n = 26), and breast cancer group with HT and HIIT (HT + HIIT, n = 26). The exercise groups underwent interval uphill walking training on a treadmill 3 times a week for 12 weeks. At the end of the study, we analyzed changes in levels of cancer-related miRs (oncomiRs) and tumour suppressor miRs (TSmiRs) in response to the HT and HIIT.
Results
In women with breast cancer versus healthy controls, the expression of some oncomiRs was significantly increased — miR-21 (P < 0.001), miR-155 (P = 0.001), miR-221 (P = 0.008), miR-27a (P < 0.001), and miR-10b (P = 0.007) — and that of some TSmiRs was significantly decreased — miR-206 (P = 0.048), miR-145 (P = 0.011), miR-143 (P = 0.008), miR-9 (P = 0.020), and let-7a (P = 0.005). Moreover, HT considerably downregulated oncomiRs and upregulated TSmiRs. HIIT for 12 weeks with HT significantly decreased the expression of the oncomiRs and significantly increased that of the TSmiRs as compared with HT alone.
Conclusions
HITT could amplify the decrease and/or increase in expression of miRs associated with HT in women with breast cancer. A prospective trial could determine whether the use of circulating miRs for monitoring treatment can be useful in therapy decisions.Permalink : ./index.php?lvl=notice_display&id=84146
in Annals of physical and rehabilitation medicine > Vol. 62, n°5 (Septembre 2019) . - p. 329-335[article] Effect of a high-intensity interval training on serum microRNA levels in women with breast cancer undergoing hormone therapy. A single-blind randomized trial [texte imprimé] / Shaban Alizadeh ; Amin Isanejad ; Sanambar Sadighi ; Solmaz Khalighfard ; Ali Mohammad Alizadeh . - 2019 . - p. 329-335.
doi.org/10.1016/j.rehab.2019.07.001
Langues : Anglais (eng)
in Annals of physical and rehabilitation medicine > Vol. 62, n°5 (Septembre 2019) . - p. 329-335
Mots-clés : microRNAs Breast cancer Hormone therapy Training Résumé : Background
The role of microRNAs (miRs) in hormone therapy (HT) is of keen interest in developing biomarkers and treatments for individuals with breast cancer. Although miRs are often moderate regulators under homeostatic conditions, their function is changed more in response to physical activity.
Objective
This single-blind randomized trial aimed to explore the effect of high-intensity interval training (HIIT) on serum levels of miRs in individuals with early-stage breast cancer undergoing HT.
Methods
Hormone receptor-positive women with breast cancer and healthy women were randomly assigned to a healthy control group (n = 15), healthy group with HIIT (n = 15), breast cancer group with HT (HT, n = 26), and breast cancer group with HT and HIIT (HT + HIIT, n = 26). The exercise groups underwent interval uphill walking training on a treadmill 3 times a week for 12 weeks. At the end of the study, we analyzed changes in levels of cancer-related miRs (oncomiRs) and tumour suppressor miRs (TSmiRs) in response to the HT and HIIT.
Results
In women with breast cancer versus healthy controls, the expression of some oncomiRs was significantly increased — miR-21 (P < 0.001), miR-155 (P = 0.001), miR-221 (P = 0.008), miR-27a (P < 0.001), and miR-10b (P = 0.007) — and that of some TSmiRs was significantly decreased — miR-206 (P = 0.048), miR-145 (P = 0.011), miR-143 (P = 0.008), miR-9 (P = 0.020), and let-7a (P = 0.005). Moreover, HT considerably downregulated oncomiRs and upregulated TSmiRs. HIIT for 12 weeks with HT significantly decreased the expression of the oncomiRs and significantly increased that of the TSmiRs as compared with HT alone.
Conclusions
HITT could amplify the decrease and/or increase in expression of miRs associated with HT in women with breast cancer. A prospective trial could determine whether the use of circulating miRs for monitoring treatment can be useful in therapy decisions.Permalink : ./index.php?lvl=notice_display&id=84146 Exemplaires (1)
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Exclu du prêtHome-based training of rhythmic skills with a serious game in Parkinson's disease: Usability and acceptability / Celia Dauvergne in Annals of physical and rehabilitation medicine, Vol. 61, n°6 (Novembre 2018)
[article]
Titre : Home-based training of rhythmic skills with a serious game in Parkinson's disease: Usability and acceptability Type de document : texte imprimé Auteurs : Celia Dauvergne ; Valentin Bégel ; Christian Gény ; et al. Année de publication : 2018 Article en page(s) : p. 380-385 Note générale : Doi : 10.1016/j.rehab.2018.08.002 Langues : Anglais (eng) Mots-clés : Serious games Training Rehabilitation Parkinson disease Beat perception Synchronization Rhythmic skills Résumé : Highlights
A music-based serious game (SG) can be used for at-home training of rhythmic skills in patients with Parkinson disease.
The proposed game (Rhythm Workers) shows good to excellent suitability.
SGs are promising for successful rehabilitation of rhythmic abilities in patients with Parkinson disease.
Abstract
Objectives
To evaluate the adherence, usability and acceptance of a rehabilitation protocol with a music-based serious game (SG) and its effect on rhythmic skills in Parkinson disease (PD).
Methods
Sixteen PD patients with mild cognitive and motor impairments were included (mean [SD] age 65 [7.28] years and Hoehn & Yahr score 2–3). Rehabilitation consisted of a 6-week at-home training program targeting rhythmic skills with a dedicated SG, Rhythm Workers, implemented on a tablet device. Patients were asked to play the game at least 30min, 3 times a week. Two half-day evaluations were conducted before and after rehabilitation. Time played and average game scores were recorded. Suitability was evaluated by a questionnaire inspired by the Suitability Evaluation Questionnaire (SEQ) and rhythmic skills by the Beat Alignment Test from the Battery for the Assessment of Auditory Sensorimotor and Timing Abilities (BAASTA).
Results
Patients played a mean (SD) of 313 (243) min, namely 57.9% of the expected time; the mean game score was 48.8/100 (19.5). The mean SEQ score for 12 patients was 29.2/45 (8.2); suitability was good to excellent for 10 patients. Beat perception reflecting rhythmic skills improved significantly in all but 5 patients.
Conclusion
This study showed good to excellent suitability of an SG used on a tablet interface for rhythmic training in PD and the feasibility of this type of training in this population.Permalink : ./index.php?lvl=notice_display&id=82388
in Annals of physical and rehabilitation medicine > Vol. 61, n°6 (Novembre 2018) . - p. 380-385[article] Home-based training of rhythmic skills with a serious game in Parkinson's disease: Usability and acceptability [texte imprimé] / Celia Dauvergne ; Valentin Bégel ; Christian Gény ; et al. . - 2018 . - p. 380-385.
Doi : 10.1016/j.rehab.2018.08.002
Langues : Anglais (eng)
in Annals of physical and rehabilitation medicine > Vol. 61, n°6 (Novembre 2018) . - p. 380-385
Mots-clés : Serious games Training Rehabilitation Parkinson disease Beat perception Synchronization Rhythmic skills Résumé : Highlights
A music-based serious game (SG) can be used for at-home training of rhythmic skills in patients with Parkinson disease.
The proposed game (Rhythm Workers) shows good to excellent suitability.
SGs are promising for successful rehabilitation of rhythmic abilities in patients with Parkinson disease.
Abstract
Objectives
To evaluate the adherence, usability and acceptance of a rehabilitation protocol with a music-based serious game (SG) and its effect on rhythmic skills in Parkinson disease (PD).
Methods
Sixteen PD patients with mild cognitive and motor impairments were included (mean [SD] age 65 [7.28] years and Hoehn & Yahr score 2–3). Rehabilitation consisted of a 6-week at-home training program targeting rhythmic skills with a dedicated SG, Rhythm Workers, implemented on a tablet device. Patients were asked to play the game at least 30min, 3 times a week. Two half-day evaluations were conducted before and after rehabilitation. Time played and average game scores were recorded. Suitability was evaluated by a questionnaire inspired by the Suitability Evaluation Questionnaire (SEQ) and rhythmic skills by the Beat Alignment Test from the Battery for the Assessment of Auditory Sensorimotor and Timing Abilities (BAASTA).
Results
Patients played a mean (SD) of 313 (243) min, namely 57.9% of the expected time; the mean game score was 48.8/100 (19.5). The mean SEQ score for 12 patients was 29.2/45 (8.2); suitability was good to excellent for 10 patients. Beat perception reflecting rhythmic skills improved significantly in all but 5 patients.
Conclusion
This study showed good to excellent suitability of an SG used on a tablet interface for rhythmic training in PD and the feasibility of this type of training in this population.Permalink : ./index.php?lvl=notice_display&id=82388 Exemplaires (1)
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Exclu du prêtA method to assess relative preference for training and environmental enrichment in captive wolves (Canis Lupus and Canis Lupus Arctos) / N. DOREY in Zoobiology, 6/34 (November/December 2015)
[article]
Titre : A method to assess relative preference for training and environmental enrichment in captive wolves (Canis Lupus and Canis Lupus Arctos) Type de document : texte imprimé Auteurs : N. DOREY, Auteur ; et coll., Auteur Année de publication : 2015 Article en page(s) : 513-517 Langues : Anglais (eng) Mots-clés : LOUP COMPORTEMENT ENRICHISSEMENT: ENVIRONNEMENTAL RENFORCEMENT :POSITIF TRAINING EVALUATION Permalink : ./index.php?lvl=notice_display&id=66180
in Zoobiology > 6/34 (November/December 2015) . - 513-517[article] A method to assess relative preference for training and environmental enrichment in captive wolves (Canis Lupus and Canis Lupus Arctos) [texte imprimé] / N. DOREY, Auteur ; et coll., Auteur . - 2015 . - 513-517.
Langues : Anglais (eng)
in Zoobiology > 6/34 (November/December 2015) . - 513-517
Mots-clés : LOUP COMPORTEMENT ENRICHISSEMENT: ENVIRONNEMENTAL RENFORCEMENT :POSITIF TRAINING EVALUATION Permalink : ./index.php?lvl=notice_display&id=66180 Réservation
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DisponibleMise en place de training et d'enrichissements du milieu en aquarium / Ludovic Revercez
Titre : Mise en place de training et d'enrichissements du milieu en aquarium Type de document : TFE / Mémoire Auteurs : Ludovic Revercez ; Laetitia Giordano, Directeur de la recherche Année de publication : 2018 Note générale : Le fichier numérique de ce document est disponible uniquement pour les membres de la Haute Ecole Louvain-en-Hainaut ainsi que ses étudiants. Veuillez-vous connecter pour accéder à votre compte lecteur Langues : Français (fre) Mots-clés : Agronomie TA Aquarium-Muséum Universitaire de Liège training raie chien de mer de corail sole mérou enrichissement du milieu Index. décimale : TFE Technologie animalière TFE Technologie animalière Permalink : ./index.php?lvl=notice_display&id=66052 Mise en place de training et d'enrichissements du milieu en aquarium [TFE / Mémoire] / Ludovic Revercez ; Laetitia Giordano, Directeur de la recherche . - 2018.
Le fichier numérique de ce document est disponible uniquement pour les membres de la Haute Ecole Louvain-en-Hainaut ainsi que ses étudiants. Veuillez-vous connecter pour accéder à votre compte lecteur
Langues : Français (fre)
Mots-clés : Agronomie TA Aquarium-Muséum Universitaire de Liège training raie chien de mer de corail sole mérou enrichissement du milieu Index. décimale : TFE Technologie animalière TFE Technologie animalière Permalink : ./index.php?lvl=notice_display&id=66052 Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Self-Administered, Home-Based SMART (Sensorimotor Active Rehabilitation Training) Arm Training: A Single-Case Report / Kathryn S. Hayward in American Journal of Occupational Therapy, Vol. 69/4 (Juillet-Août 2015)
[article]
Titre : Self-Administered, Home-Based SMART (Sensorimotor Active Rehabilitation Training) Arm Training: A Single-Case Report Type de document : texte imprimé Auteurs : Kathryn S. Hayward, Auteur ; Bridee A. Neibling, Auteur ; Ruth N. Barker, Auteur Année de publication : 2015 Article en page(s) : 6904210020p1-6904210020p8 Langues : Anglais (eng) Mots-clés : Arm cerebrovascular accident ischemic stroke rehabilitation self administration training Résumé : This single-case, mixed-method study explored the feasibility of self-administered, home-based SMART (sensorimotor active rehabilitation training) Arm training for a 57-yr-old man with severe upper-limb disability after a right frontoparietal hemorrhagic stroke 9 mo earlier. Over 4 wk of self-administered, home-based SMART Arm training, the participant completed 2,100 repetitions unassisted. His wife provided support for equipment set-up and training progressions. Clinically meaningful improvements in arm impairment (strength), activity (arm and hand tasks), and participation (use of arm in everyday tasks) occurred after training (at 4 wk) and at follow-up (at 16 wk). Areas for refinement of SMART Arm training derived from thematic analysis of the participant’s and researchers’ journals focused on enabling independence, ensuring home and user friendliness, maintaining the motivation to persevere, progressing toward everyday tasks, and integrating practice into daily routine. These findings suggest that further investigation of self-administered, home-based SMART Arm training is warranted for people with stroke who have severe upper-limb disability. Permalink : ./index.php?lvl=notice_display&id=40414
in American Journal of Occupational Therapy > Vol. 69/4 (Juillet-Août 2015) . - 6904210020p1-6904210020p8[article] Self-Administered, Home-Based SMART (Sensorimotor Active Rehabilitation Training) Arm Training: A Single-Case Report [texte imprimé] / Kathryn S. Hayward, Auteur ; Bridee A. Neibling, Auteur ; Ruth N. Barker, Auteur . - 2015 . - 6904210020p1-6904210020p8.
Langues : Anglais (eng)
in American Journal of Occupational Therapy > Vol. 69/4 (Juillet-Août 2015) . - 6904210020p1-6904210020p8
Mots-clés : Arm cerebrovascular accident ischemic stroke rehabilitation self administration training Résumé : This single-case, mixed-method study explored the feasibility of self-administered, home-based SMART (sensorimotor active rehabilitation training) Arm training for a 57-yr-old man with severe upper-limb disability after a right frontoparietal hemorrhagic stroke 9 mo earlier. Over 4 wk of self-administered, home-based SMART Arm training, the participant completed 2,100 repetitions unassisted. His wife provided support for equipment set-up and training progressions. Clinically meaningful improvements in arm impairment (strength), activity (arm and hand tasks), and participation (use of arm in everyday tasks) occurred after training (at 4 wk) and at follow-up (at 16 wk). Areas for refinement of SMART Arm training derived from thematic analysis of the participant’s and researchers’ journals focused on enabling independence, ensuring home and user friendliness, maintaining the motivation to persevere, progressing toward everyday tasks, and integrating practice into daily routine. These findings suggest that further investigation of self-administered, home-based SMART Arm training is warranted for people with stroke who have severe upper-limb disability. Permalink : ./index.php?lvl=notice_display&id=40414 Exemplaires (1)
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Exclu du prêtUpper-Limb Rehabilitation With Adaptive Video Games for Preschool Children With Developmental Disabilities / Hsieh-Chun Hsieh in American Journal of Occupational Therapy, Vol. 69/4 (Juillet-Août 2015)
PermalinkL’entrainement médical des phoques (Halichoerus grypus, Phoca vitulina, Pagophilus groenlandicus, Pusa hispida) et des otaries (Zalophus californasus) à Océanopolis : des bases de l’entrainement aux exercices complexes / Elise PETERS
PermalinkExploring player communication in interactions with sport officials / Ian Cunningham in Science & motricité, 87 (Avril 2015)
PermalinkMatch performances of soccer referees: the role of sports science / Matthew Weston in Science & motricité, 87 (Avril 2015)
PermalinkZoom sur l'éducation au clickertraining / Isabelle Vieira in L'auxiliaire vétérinaire, 106 (Janvier-février 2016)
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