[article] 
inLabAnimal > Vol. 21 N°11 (November 2021) . - p. 31-34

Titre :	Know Your Model: A brief history of making mutant mouse genetic models
Type de document :	texte imprimé
Auteurs :	Susan M. Bello ; Michelle N. Perry ; Cynthia L. Smith
Année de publication :	2021
Article en page(s) :	p. 31-34
Langues :	Anglais (eng)
Mots-clés :	Animals  Mice  Models, Genetic*
Résumé :	For over a century, researchers have used mice as models and adapted many new methods to create novel mutations in them. In the past 100+ years, we have gone from breeding strains for selected traits to inducing random mutations throughout the genome to creating designer alleles with multiple functions. Each method offers opportunities and challenges for researchers as they try to address specific research questions with mouse models.
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[article] Know Your Model: A brief history of making mutant mouse genetic models [texte imprimé] / Susan M. Bello ; Michelle N. Perry ; Cynthia L. Smith . - 2021 . - p. 31-34.
Langues : Anglais (eng)
in LabAnimal > Vol. 21 N°11 (November 2021) . - p. 31-34

Mots-clés :	Animals  Mice  Models, Genetic*
Résumé :	For over a century, researchers have used mice as models and adapted many new methods to create novel mutations in them. In the past 100+ years, we have gone from breeding strains for selected traits to inducing random mutations throughout the genome to creating designer alleles with multiple functions. Each method offers opportunities and challenges for researchers as they try to address specific research questions with mouse models.
Permalink :	./index.php?lvl=notice_display&id=98140