[article] 
inLabAnimal > 03/21 (mars 2021) . - p. 16-20

Titre :	Model matchmaking
Type de document :	texte imprimé
Auteurs :	Ellen P. Neff
Année de publication :	2021
Article en page(s) :	p. 16-20
Langues :	Anglais (eng)
Résumé :	Building platforms to connect clinicians and model organism researchers. What do a child with a heart defect and a fruit fly with notched wings have in common? The answer may not be obvious at a glance, but the aberrant phenotypes share genetic pathways1. But unlike a patient, that fly can be manipulated with an ever-growing number of genetic tools and tested with different assays to tease apart pathogenic mechanisms, while scores and scores of flies can be quickly dosed with potential therapeutics in attempts to rescue an anomalous phenotype. The same can increasingly be said of zebrafish, C. elegans worms, mice and frogs and other model organisms deployed in research labs around the world.
En ligne :	https://www.nature.com/articles/s41684-020-00706-7
Permalink :	./index.php?lvl=notice_display&id=92722

[article] Model matchmaking [texte imprimé] / Ellen P. Neff . - 2021 . - p. 16-20.
Langues : Anglais (eng)
in LabAnimal > 03/21 (mars 2021) . - p. 16-20

Résumé :	Building platforms to connect clinicians and model organism researchers. What do a child with a heart defect and a fruit fly with notched wings have in common? The answer may not be obvious at a glance, but the aberrant phenotypes share genetic pathways1. But unlike a patient, that fly can be manipulated with an ever-growing number of genetic tools and tested with different assays to tease apart pathogenic mechanisms, while scores and scores of flies can be quickly dosed with potential therapeutics in attempts to rescue an anomalous phenotype. The same can increasingly be said of zebrafish, C. elegans worms, mice and frogs and other model organisms deployed in research labs around the world.
En ligne :	https://www.nature.com/articles/s41684-020-00706-7
Permalink :	./index.php?lvl=notice_display&id=92722