Acquired Fanconi syndrome uncovered atypical inclusions in neoplastic plasma cells / Radu Chiriac in Annales de Biologie Clinique, Vol.83 N°1 (mars 2025)

Public ISBD [article]  inAnnales de Biologie Clinique > Vol.83 N°1 (mars 2025) . - p. 101-102 Titre : Acquired Fanconi syndrome uncovered atypical inclusions in neoplastic plasma cells Titre original : Le syndrome de Fanconi acquis a révélé des inclusions atypiques dans les plasmocytes néoplasiques Type de document : texte imprimé Auteurs : Radu Chiriac ; Zofia Gross Année de publication : 2025 Article en page(s) : p. 101-102 Note générale : DOI : 10.1684/abc.2025.1941 Langues : Anglais (eng) Mots-clés : Maladie rénale  syndrome de Fanconi acquis Résumé : A man in his 50s presented with thirst, fatigue, muscle weakness, and polyuria, worsening over one week. A humerus fracture was reported two months ago. There was no history of drug abuse, medication use, or other relevant medical conditions.Laboratory investigations revealed hypokalemia (1.5 mmol/L; range 3,5-5 mmol/L), hypophosphatemia (0.5 mmol/L; range 0,9-1,5 mmol/L), and hyperchloremic metabolic acidosis. Additionally, increased 24-hour urinary excretion of phosphate, bicarbonate, calcium, [...] Permalink : ./index.php?lvl=notice_display&id=123476 [article] Acquired Fanconi syndrome uncovered atypical inclusions in neoplastic plasma cells = Le syndrome de Fanconi acquis a révélé des inclusions atypiques dans les plasmocytes néoplasiques [texte imprimé] / Radu Chiriac ; Zofia Gross . - 2025 . - p. 101-102. DOI : 10.1684/abc.2025.1941 Langues : Anglais (eng) in Annales de Biologie Clinique > Vol.83 N°1 (mars 2025) . - p. 101-102 Mots-clés : Maladie rénale  syndrome de Fanconi acquis Résumé : A man in his 50s presented with thirst, fatigue, muscle weakness, and polyuria, worsening over one week. A humerus fracture was reported two months ago. There was no history of drug abuse, medication use, or other relevant medical conditions.Laboratory investigations revealed hypokalemia (1.5 mmol/L; range 3,5-5 mmol/L), hypophosphatemia (0.5 mmol/L; range 0,9-1,5 mmol/L), and hyperchloremic metabolic acidosis. Additionally, increased 24-hour urinary excretion of phosphate, bicarbonate, calcium, [...] Permalink : ./index.php?lvl=notice_display&id=123476

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Les perles du myélome : corps de Russell et cellules de Mott / Radu Chiriac in Annales de Biologie Clinique, Vol.82 N°6 (Novembre-décembre 2024)

Public ISBD [article]  inAnnales de Biologie Clinique > Vol.82 N°6 (Novembre-décembre 2024) . - p. 663-664 Titre : Les perles du myélome : corps de Russell et cellules de Mott Titre original : The pearls of myeloma : Russel bodies and Mott cells Type de document : texte imprimé Auteurs : Radu Chiriac ; Zofia Gross Année de publication : 2024 Article en page(s) : p. 663-664 Note générale : DOI : 10.1684/abc.2024.1936 Langues : Anglais (eng) Résumé : A man in his 50s presented with worsening dyspnea and confusion. Initial blood work revealed only anemia (60 g/L) without abnormal circulating cells. Additionally, a serum IgG (kappa) monoclonal protein at 35 g/L was detected. In light of these findings, a bone marrow aspirate was performed, and microscopic examination revealed infiltration by atypical plasma cells (70%). Numerous Russell bodies, giving the plasma cells a berry-like appearance, known as Mott cells, were observed, as well as binucleated [...] Permalink : ./index.php?lvl=notice_display&id=122789 [article] Les perles du myélome : corps de Russell et cellules de Mott = The pearls of myeloma : Russel bodies and Mott cells [texte imprimé] / Radu Chiriac ; Zofia Gross . - 2024 . - p. 663-664. DOI : 10.1684/abc.2024.1936 Langues : Anglais (eng) in Annales de Biologie Clinique > Vol.82 N°6 (Novembre-décembre 2024) . - p. 663-664 Résumé : A man in his 50s presented with worsening dyspnea and confusion. Initial blood work revealed only anemia (60 g/L) without abnormal circulating cells. Additionally, a serum IgG (kappa) monoclonal protein at 35 g/L was detected. In light of these findings, a bone marrow aspirate was performed, and microscopic examination revealed infiltration by atypical plasma cells (70%). Numerous Russell bodies, giving the plasma cells a berry-like appearance, known as Mott cells, were observed, as well as binucleated [...] Permalink : ./index.php?lvl=notice_display&id=122789

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