Short interval or continuous training programs to improve walking distance for intermittent claudication : Pilot study / Béatrice Villemur in Annals of physical and rehabilitation medicine, Vol. 63, n°6 (November 20)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 63, n°6 (November 20) . - p. 466-473 Titre : Short interval or continuous training programs to improve walking distance for intermittent claudication : Pilot study Type de document : texte imprimé Auteurs : Béatrice Villemur ; Béatrice Thoreau ; Michel Guinot ; Elodie Gailledrat ; Véronique Evra ; Céline Vermorel ; Alison Foote ; Patrick Carpentier ; Jean-Luc Bosson ; Dominic Pérennou Année de publication : 2020 Article en page(s) : p. 466-473 Note générale : doi.org/10.1016/j.rehab.2020.03.004 Langues : Anglais (eng) Mots-clés : Peripheral arterial disease  Intermittent claudication  Physical therapy  Exercise physiology  Treadmill training with active recovery  Supervised exercise Résumé : Objective Supervised exercise training is part of first-line therapies for intermittent claudication. Short periods of intensive treadmill training have been found efficient; however, the optimal modalities remain to be determined, especially interval training with active recovery (ITAR). In this prospective assessor-blinded single-centre pilot study, we assessed the feasibility of a randomised controlled trial comparing parallel 4-week intensive rehabilitation programs comprising treadmill training performed as ITAR or conventional training with constant slope and speed interspersed with rest periods (CT). Methods A total of 38 in- or out-patients were randomised to the ITAR or CT program for 5 days/week for 4 weeks. The primary outcome was change in maximum walking distance measured on a graded treadmill before and after the program. Results Adherence was high. All training sessions were completed in the ITAR program and only a few were not completed in the CT program (median 100% [Q1–Q3 96–100]). Tolerance was excellent (no adverse events). VO2peak was low in both groups, corresponding to moderate to severe exercise intolerance. The 2 groups did not differ in the primary outcome (median ITAR vs CT 480 [135–715] vs 315 m [0–710]; p = 0.62) or other walking distances (constant speed and gradient treadmill test). For all 38 participants, both programs greatly increased maximum walking distance in the graded treadmill test: median 415 [240–650] to 995 m [410–1490], with a large effect size (p < 10−4). Conclusion A 4-week intensive rehabilitation program with ITAR or CT for intermittent claudication showed high adherence, was well tolerated, and improved walking distance as much as that reported for longer conventional programs. These findings prompt the design of a larger multicenter randomised controlled trial. Permalink : ./index.php?lvl=notice_display&id=91322 [article] Short interval or continuous training programs to improve walking distance for intermittent claudication : Pilot study [texte imprimé] / Béatrice Villemur ; Béatrice Thoreau ; Michel Guinot ; Elodie Gailledrat ; Véronique Evra ; Céline Vermorel ; Alison Foote ; Patrick Carpentier ; Jean-Luc Bosson ; Dominic Pérennou . - 2020 . - p. 466-473. doi.org/10.1016/j.rehab.2020.03.004 Langues : Anglais (eng) in Annals of physical and rehabilitation medicine > Vol. 63, n°6 (November 20) . - p. 466-473 Mots-clés : Peripheral arterial disease  Intermittent claudication  Physical therapy  Exercise physiology  Treadmill training with active recovery  Supervised exercise Résumé : Objective Supervised exercise training is part of first-line therapies for intermittent claudication. Short periods of intensive treadmill training have been found efficient; however, the optimal modalities remain to be determined, especially interval training with active recovery (ITAR). In this prospective assessor-blinded single-centre pilot study, we assessed the feasibility of a randomised controlled trial comparing parallel 4-week intensive rehabilitation programs comprising treadmill training performed as ITAR or conventional training with constant slope and speed interspersed with rest periods (CT). Methods A total of 38 in- or out-patients were randomised to the ITAR or CT program for 5 days/week for 4 weeks. The primary outcome was change in maximum walking distance measured on a graded treadmill before and after the program. Results Adherence was high. All training sessions were completed in the ITAR program and only a few were not completed in the CT program (median 100% [Q1–Q3 96–100]). Tolerance was excellent (no adverse events). VO2peak was low in both groups, corresponding to moderate to severe exercise intolerance. The 2 groups did not differ in the primary outcome (median ITAR vs CT 480 [135–715] vs 315 m [0–710]; p = 0.62) or other walking distances (constant speed and gradient treadmill test). For all 38 participants, both programs greatly increased maximum walking distance in the graded treadmill test: median 415 [240–650] to 995 m [410–1490], with a large effect size (p < 10−4). Conclusion A 4-week intensive rehabilitation program with ITAR or CT for intermittent claudication showed high adherence, was well tolerated, and improved walking distance as much as that reported for longer conventional programs. These findings prompt the design of a larger multicenter randomised controlled trial. Permalink : ./index.php?lvl=notice_display&id=91322

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