When all is not lost: considering genetic compensation in laboratory animals / Rosie K. A. Bunton-Stasyshyn in LabAnimal, 11/19 (Novembre 2019)

Public ISBD [article]  inLabAnimal > 11/19 (Novembre 2019) . - p. 20-23 Titre : When all is not lost: considering genetic compensation in laboratory animals Type de document : texte imprimé Auteurs : Rosie K. A. Bunton-Stasyshyn ; Sara Wells ; Lydia Teboul Année de publication : 2019 Article en page(s) : p. 20-23 Langues : Anglais (eng) Résumé : A recent article by El-Brolosy and colleagues introduced an unexpected twist for our understanding of knock-out mutations by revealing compensatory mechanisms that recruit the expression of other genes to mitigate the consequences of the mutation. We discuss the main findings of the paper and their impact for our interpretations of the effects of mutations in laboratory animals and humans. Permalink : ./index.php?lvl=notice_display&id=82067 [article] When all is not lost: considering genetic compensation in laboratory animals [texte imprimé] / Rosie K. A. Bunton-Stasyshyn ; Sara Wells ; Lydia Teboul . - 2019 . - p. 20-23. Langues : Anglais (eng) in LabAnimal > 11/19 (Novembre 2019) . - p. 20-23 Résumé : A recent article by El-Brolosy and colleagues introduced an unexpected twist for our understanding of knock-out mutations by revealing compensatory mechanisms that recruit the expression of other genes to mitigate the consequences of the mutation. We discuss the main findings of the paper and their impact for our interpretations of the effects of mutations in laboratory animals and humans. Permalink : ./index.php?lvl=notice_display&id=82067

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