Effect of exercise training on left ventricular mechanics after acute myocardial infarction–an exploratory study / Gordon McGregor in Annals of physical and rehabilitation medicine, Vol. 61, n°3 (Mai 2018)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 61, n°3 (Mai 2018) . - p. 119-124 Titre : Effect of exercise training on left ventricular mechanics after acute myocardial infarction–an exploratory study Type de document : texte imprimé Auteurs : Gordon McGregor ; Eric Stöhr ; David Oxborough ; Peter Kimani ; Rob Shave Année de publication : 2018 Article en page(s) : p. 119-124 Note générale : Doi : 10.1016/j.rehab.2018.01.003 Langues : Anglais (eng) Mots-clés : Longitudinal strain  Left ventricular twist  Left ventricular remodelling Résumé : Background Cardiac rehabilitation (CR) exercise training is beneficial after myocardial infarction (MI). Whilst the peripheral adaptations to training are well defined, little is known regarding the effect on left ventricular (LV) remodelling, particularly LV function. Efficient LV ejection and filling is achieved through deformation and rotation of the myocardium in systole and diastole – LV mechanics. The response of LV mechanics to CR exercise training in MI patients is unknown. Methods In this observational exploratory study, 36 (of 40 enrolled) male, MI patients completed either 10-weeks of twice-weekly gym based cardiovascular exercise at 60–80% VO2peak (n=18), or a non-exercise control period (n=18). Cardiopulmonary exercise testing and speckle tracking echocardiography were performed at baseline and 10 weeks. Results Compared to the non-exercise group, VO2peak improved with CR exercise training (Difference: +4.28 [95% CI: 1.34 to 7.23] ml.kg−1.min−1, P=0.01). Neither conventional LV structural or functional indices, nor LV global longitudinal strain, significantly changed in either group. In contrast, LV twist and twist velocity decreased in the exercise group and increased in the non-exercise group (Difference: −3.95° [95% CI: −7.92 to 0.03°], P=0.05 and −19.2°.s−1 [95% CI: −35.9 to −2.7°.s−1], P=0.02, respectively). Conclusion In MI patients who completed CR exercise training, LV twist and twist velocity decreased, whereas these parameters increased in patients who did not exercise. These preliminary data may indicate reverse LV functional remodelling and improved functional reserve. The assessment of LV twist may serve as an indicator of the therapeutic ben Permalink : ./index.php?lvl=notice_display&id=80458 [article] Effect of exercise training on left ventricular mechanics after acute myocardial infarction–an exploratory study [texte imprimé] / Gordon McGregor ; Eric Stöhr ; David Oxborough ; Peter Kimani ; Rob Shave . - 2018 . - p. 119-124. Doi : 10.1016/j.rehab.2018.01.003 Langues : Anglais (eng) in Annals of physical and rehabilitation medicine > Vol. 61, n°3 (Mai 2018) . - p. 119-124 Mots-clés : Longitudinal strain  Left ventricular twist  Left ventricular remodelling Résumé : Background Cardiac rehabilitation (CR) exercise training is beneficial after myocardial infarction (MI). Whilst the peripheral adaptations to training are well defined, little is known regarding the effect on left ventricular (LV) remodelling, particularly LV function. Efficient LV ejection and filling is achieved through deformation and rotation of the myocardium in systole and diastole – LV mechanics. The response of LV mechanics to CR exercise training in MI patients is unknown. Methods In this observational exploratory study, 36 (of 40 enrolled) male, MI patients completed either 10-weeks of twice-weekly gym based cardiovascular exercise at 60–80% VO2peak (n=18), or a non-exercise control period (n=18). Cardiopulmonary exercise testing and speckle tracking echocardiography were performed at baseline and 10 weeks. Results Compared to the non-exercise group, VO2peak improved with CR exercise training (Difference: +4.28 [95% CI: 1.34 to 7.23] ml.kg−1.min−1, P=0.01). Neither conventional LV structural or functional indices, nor LV global longitudinal strain, significantly changed in either group. In contrast, LV twist and twist velocity decreased in the exercise group and increased in the non-exercise group (Difference: −3.95° [95% CI: −7.92 to 0.03°], P=0.05 and −19.2°.s−1 [95% CI: −35.9 to −2.7°.s−1], P=0.02, respectively). Conclusion In MI patients who completed CR exercise training, LV twist and twist velocity decreased, whereas these parameters increased in patients who did not exercise. These preliminary data may indicate reverse LV functional remodelling and improved functional reserve. The assessment of LV twist may serve as an indicator of the therapeutic ben Permalink : ./index.php?lvl=notice_display&id=80458

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