Exercise and insulin resistance in type 2 diabetes mellitus: A systematic review and meta-analysis / A. Sampath Kumar in Annals of physical and rehabilitation medicine, Vol. 62, n°2 (Mars 2019)  

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 62, n°2 (Mars 2019) . - p. 98-103 Titre : Exercise and insulin resistance in type 2 diabetes mellitus: A systematic review and meta-analysis Type de document : texte imprimé Auteurs : A. Sampath Kumar ; Arun G. Maiya ; B.A. Shastry ; K. Vaishali ; N. Ravishankar ; Animesh Hazari ; Shubha Gundmi ; Radhika Jadhav Année de publication : 2019 Article en page(s) : p. 98-103 Note générale : https://doi.org/10.1016/j.rehab.2018.11.001 Langues : Anglais (eng) Mots-clés : Insulin resistance  Homa-IR  Fasting insulin  Glycated hemoglobin  Type 2 diabetes mellitus  Aerobic exercise  Resistance exercise Résumé : Background Insulin resistance is a determining factor in the pathophysiology of type 2 diabetes mellitus (T2DM). Exercise is known to improve insulin resistance, but a systematic review of the literature is lacking. Objective This systematic review and meta-analysis focused on identifying evidence for the effectiveness of a structured exercise intervention program for insulin resistance in T2DM. Methods We searched MEDLINE via PubMed, CINHAL, Scopus and Web of Science, and the Cochrane Central Register of Controlled Trials for reports of studies on fasting insulin, homeostatic model assessment for insulin resistance (Homa-IR), fasting blood sugar, glycated hemoglobin and body mass index in patients with T2DM and healthy controls that were published between 1990 and 2017. Data are reported as the standardized mean difference or mean difference with 95% confidence intervals (CIs). Results Among 2242 records retrieved, only 11 full-text articles were available for meta-analysis. Data for 846 participants were analyzed, 440 in the intervention group, and 406 in the control group. The mean difference for fasting insulin level was −1.64 (95% CI; −3.38 to 0.10), Homa-Ir 0.14 (−1.48 to 1.76), fasting blood sugar −5.12 (−7.78 to −2.45), hemoglobin A1c 0.63 (−0.82 to 2.08) and body mass index −0.36 (−1.51 to 0.79). Conclusion The evidence highlights the effectiveness of a structured exercise intervention program for insulin resistance in T2DM with a moderate level 2 of evidence. En ligne : https://www.sciencedirect.com/science/article/pii/S1877065718314830 Permalink : ./index.php?lvl=notice_display&id=84104 [article] Exercise and insulin resistance in type 2 diabetes mellitus: A systematic review and meta-analysis [texte imprimé] / A. Sampath Kumar ; Arun G. Maiya ; B.A. Shastry ; K. Vaishali ; N. Ravishankar ; Animesh Hazari ; Shubha Gundmi ; Radhika Jadhav . - 2019 . - p. 98-103. https://doi.org/10.1016/j.rehab.2018.11.001 Langues : Anglais (eng) in Annals of physical and rehabilitation medicine > Vol. 62, n°2 (Mars 2019) . - p. 98-103 Mots-clés : Insulin resistance  Homa-IR  Fasting insulin  Glycated hemoglobin  Type 2 diabetes mellitus  Aerobic exercise  Resistance exercise Résumé : Background Insulin resistance is a determining factor in the pathophysiology of type 2 diabetes mellitus (T2DM). Exercise is known to improve insulin resistance, but a systematic review of the literature is lacking. Objective This systematic review and meta-analysis focused on identifying evidence for the effectiveness of a structured exercise intervention program for insulin resistance in T2DM. Methods We searched MEDLINE via PubMed, CINHAL, Scopus and Web of Science, and the Cochrane Central Register of Controlled Trials for reports of studies on fasting insulin, homeostatic model assessment for insulin resistance (Homa-IR), fasting blood sugar, glycated hemoglobin and body mass index in patients with T2DM and healthy controls that were published between 1990 and 2017. Data are reported as the standardized mean difference or mean difference with 95% confidence intervals (CIs). Results Among 2242 records retrieved, only 11 full-text articles were available for meta-analysis. Data for 846 participants were analyzed, 440 in the intervention group, and 406 in the control group. The mean difference for fasting insulin level was −1.64 (95% CI; −3.38 to 0.10), Homa-Ir 0.14 (−1.48 to 1.76), fasting blood sugar −5.12 (−7.78 to −2.45), hemoglobin A1c 0.63 (−0.82 to 2.08) and body mass index −0.36 (−1.51 to 0.79). Conclusion The evidence highlights the effectiveness of a structured exercise intervention program for insulin resistance in T2DM with a moderate level 2 of evidence. En ligne : https://www.sciencedirect.com/science/article/pii/S1877065718314830 Permalink : ./index.php?lvl=notice_display&id=84104

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Hand dysfunction in type 2 diabetes mellitus: Systematic review with meta-analysis / Shubha Gundmi in Annals of physical and rehabilitation medicine, Vol. 61, n°2 (Mars 2018)

Public ISBD [article]  inAnnals of physical and rehabilitation medicine > Vol. 61, n°2 (Mars 2018) . - p. 99-104 Titre : Hand dysfunction in type 2 diabetes mellitus: Systematic review with meta-analysis Type de document : texte imprimé Auteurs : Shubha Gundmi ; Arun G. Maiya ; Anil K. Bhat ; N. Ravishankar ; Manjunatha H. Hande ; K.V. Rajagopal Année de publication : 2018 Article en page(s) : p. 99-104 Note générale : Doi : 10.1016/j.rehab.2017.12.006 Langues : Anglais (eng) Mots-clés : Type 2 diabetes mellitus  Hand  Dysfunction  Strength, Dexterity Résumé : Background People with type 2 diabetes mellitus frequently show complications in feet and hands. However, the literature has mostly focused on foot complications. The disease can affect the strength and dexterity of the hands, thereby reducing function. Objectives This systematic review and meta-analysis focused on identifying the existing evidence on how type 2 diabetes mellitus affects hand strength, dexterity and function. Methods We searched MEDLINE via PubMed, CINHAL, Scopus and Web of Science, and the Cochrane central register of controlled trials for reports of studies of grip and pinch strength as well as hand dexterity and function evaluated by questionnaires comparing patients with type 2 diabetes mellitus and healthy controls that were published between 1990 and 2017. Data are reported as standardized mean difference (SMD) or mean difference (MD) and 95% confidence intervals (CIs). Results Among 2077 records retrieved, only 7 full-text articles were available for meta-analysis. For both the dominant and non-dominant hand, type 2 diabetes mellitus negatively affected grip strength (SMD: −1.03; 95% CI: −2.24 to 0.18 and −1.37, −3.07 to 0.33) and pinch strength (−1.09, −2.56 to 0.38 and −1.12, −2.73 to 0.49), although not significantly. Dexterity of the dominant hand did not differ between diabetes and control groups but was poorer for the non-dominant hand, although not significantly. Hand function was worse for diabetes than control groups in 2 studies (MD: −8.7; 95% CI: −16.88 to −1.52 and 4.69, 2.03 to 7.35). Conclusion This systematic review with meta-analysis suggested reduced hand function, specifically grip and pinch strength, for people with type 2 diabetes mellitus versus healthy controls. However, the sample size for all studies was low. Hence, we need studies with adequate sample size and randomized controlled trials to provide statistically significant results. Permalink : ./index.php?lvl=notice_display&id=80453 [article] Hand dysfunction in type 2 diabetes mellitus: Systematic review with meta-analysis [texte imprimé] / Shubha Gundmi ; Arun G. Maiya ; Anil K. Bhat ; N. Ravishankar ; Manjunatha H. Hande ; K.V. Rajagopal . - 2018 . - p. 99-104. Doi : 10.1016/j.rehab.2017.12.006 Langues : Anglais (eng) in Annals of physical and rehabilitation medicine > Vol. 61, n°2 (Mars 2018) . - p. 99-104 Mots-clés : Type 2 diabetes mellitus  Hand  Dysfunction  Strength, Dexterity Résumé : Background People with type 2 diabetes mellitus frequently show complications in feet and hands. However, the literature has mostly focused on foot complications. The disease can affect the strength and dexterity of the hands, thereby reducing function. Objectives This systematic review and meta-analysis focused on identifying the existing evidence on how type 2 diabetes mellitus affects hand strength, dexterity and function. Methods We searched MEDLINE via PubMed, CINHAL, Scopus and Web of Science, and the Cochrane central register of controlled trials for reports of studies of grip and pinch strength as well as hand dexterity and function evaluated by questionnaires comparing patients with type 2 diabetes mellitus and healthy controls that were published between 1990 and 2017. Data are reported as standardized mean difference (SMD) or mean difference (MD) and 95% confidence intervals (CIs). Results Among 2077 records retrieved, only 7 full-text articles were available for meta-analysis. For both the dominant and non-dominant hand, type 2 diabetes mellitus negatively affected grip strength (SMD: −1.03; 95% CI: −2.24 to 0.18 and −1.37, −3.07 to 0.33) and pinch strength (−1.09, −2.56 to 0.38 and −1.12, −2.73 to 0.49), although not significantly. Dexterity of the dominant hand did not differ between diabetes and control groups but was poorer for the non-dominant hand, although not significantly. Hand function was worse for diabetes than control groups in 2 studies (MD: −8.7; 95% CI: −16.88 to −1.52 and 4.69, 2.03 to 7.35). Conclusion This systematic review with meta-analysis suggested reduced hand function, specifically grip and pinch strength, for people with type 2 diabetes mellitus versus healthy controls. However, the sample size for all studies was low. Hence, we need studies with adequate sample size and randomized controlled trials to provide statistically significant results. Permalink : ./index.php?lvl=notice_display&id=80453

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