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Updates from the aquarium : considering genetic compensation biocontainment gets big
Mention de date : Novembre 2019
Paru le : 01/11/2019
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[article]
| Titre : |
A zebrafish genetic model enables an invaluable discovery: a lifesaving treatment for a lymphatic anomaly |
| Type de document : |
texte imprimé |
| Auteurs : |
Katarzyna Koltowska |
| Année de publication : |
2019 |
| Article en page(s) : |
p. 16-18 |
| Langues : |
Anglais (eng) |
| Résumé : |
In medical research, treatments are often thought of as moving “from bench to bedside.” A new study identifies a specific treatment in zebrafish and brings it to a patient, highlighting the role of these animal models in personalized medicine. |
| Permalink : |
./index.php?lvl=notice_display&id=82066 |
in LabAnimal > 11/19 (Novembre 2019) . - p. 16-18
[article] A zebrafish genetic model enables an invaluable discovery: a lifesaving treatment for a lymphatic anomaly [texte imprimé] / Katarzyna Koltowska . - 2019 . - p. 16-18. Langues : Anglais ( eng) in LabAnimal > 11/19 (Novembre 2019) . - p. 16-18
| Résumé : |
In medical research, treatments are often thought of as moving “from bench to bedside.” A new study identifies a specific treatment in zebrafish and brings it to a patient, highlighting the role of these animal models in personalized medicine. |
| Permalink : |
./index.php?lvl=notice_display&id=82066 |
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[article]
| Titre : |
When all is not lost: considering genetic compensation in laboratory animals |
| Type de document : |
texte imprimé |
| Auteurs : |
Rosie K. A. Bunton-Stasyshyn ; Sara Wells ; Lydia Teboul |
| Année de publication : |
2019 |
| Article en page(s) : |
p. 20-23 |
| Langues : |
Anglais (eng) |
| Résumé : |
A recent article by El-Brolosy and colleagues introduced an unexpected twist for our understanding of knock-out mutations by revealing compensatory mechanisms that recruit the expression of other genes to mitigate the consequences of the mutation. We discuss the main findings of the paper and their impact for our interpretations of the effects of mutations in laboratory animals and humans. |
| Permalink : |
./index.php?lvl=notice_display&id=82067 |
in LabAnimal > 11/19 (Novembre 2019) . - p. 20-23
[article] When all is not lost: considering genetic compensation in laboratory animals [texte imprimé] / Rosie K. A. Bunton-Stasyshyn ; Sara Wells ; Lydia Teboul . - 2019 . - p. 20-23. Langues : Anglais ( eng) in LabAnimal > 11/19 (Novembre 2019) . - p. 20-23
| Résumé : |
A recent article by El-Brolosy and colleagues introduced an unexpected twist for our understanding of knock-out mutations by revealing compensatory mechanisms that recruit the expression of other genes to mitigate the consequences of the mutation. We discuss the main findings of the paper and their impact for our interpretations of the effects of mutations in laboratory animals and humans. |
| Permalink : |
./index.php?lvl=notice_display&id=82067 |
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[article]
| Titre : |
Keeping large animals contained |
| Type de document : |
texte imprimé |
| Auteurs : |
Ellen P. Neff |
| Année de publication : |
2019 |
| Article en page(s) : |
p. 27-29 |
| Langues : |
Anglais (eng) |
| Résumé : |
Caring for lab animals is always a priority. But some, depending on the research they are being used for, can require extra attention. As the animals in question get bigger, the task of keeping them in contained facilities can just get a bit more challenging. |
| Permalink : |
./index.php?lvl=notice_display&id=82069 |
in LabAnimal > 11/19 (Novembre 2019) . - p. 27-29
[article] Keeping large animals contained [texte imprimé] / Ellen P. Neff . - 2019 . - p. 27-29. Langues : Anglais ( eng) in LabAnimal > 11/19 (Novembre 2019) . - p. 27-29
| Résumé : |
Caring for lab animals is always a priority. But some, depending on the research they are being used for, can require extra attention. As the animals in question get bigger, the task of keeping them in contained facilities can just get a bit more challenging. |
| Permalink : |
./index.php?lvl=notice_display&id=82069 |
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