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Focus on diabetes Mention de date : Décembre 2009
Paru le : 01/12/2009
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Revue | Revue | Centre de Documentation HELHa Campus Montignies | Réserve | Consultable sur demande auprès des documentalistes Exclu du prêt |
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Exemplaires (1)
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Revue | Revue | Centre de Documentation HELHa Campus Montignies | Réserve | Consultable sur demande auprès des documentalistes Exclu du prêt |
[article]
Titre : |
Simulating the fine-branch arboreal niche and exercising mice to elicit above-branch quadrupedal grasping and climbing. |
Type de document : |
texte imprimé |
Auteurs : |
Craig D. Byron |
Année de publication : |
2009 |
Article en page(s) : |
p. 34-40 |
Langues : |
Anglais (eng) |
Résumé : |
The fine-branch niche is a natural setting found among the slender vines and terminal branches of shrubs and tree canopies. In this study, the authors designed two simulations of this setting for laboratory mice. Their main goal was to model phenotypic plasticity in a small, clawed mammal, in order to better understand the effect of a thin-branch arboreal setting on musculoskeletal growth and behavior of these animals. The authors exposed mice to the smaller climbing setting for limited amounts of time (e.g., 30 min) and used the larger setting to permanently house another group of mice. Mice in both the limited and continuous climbing groups succeeded at quadrupedal climbing among a complex of thin branch segments. This led the authors to postulate that similarly sized pre-primates that lacked the unique features of today's primates could potentially have exploited this niche. The mice housed in the continuous model remained healthy and showed no signs of aggression, leading the authors to suggest that animal care personnel could use similar models as forms of enrichment for laboratory mice. |
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in LabAnimal-Europe > 12/09 (Décembre 2009) . - p. 34-40
[article] Simulating the fine-branch arboreal niche and exercising mice to elicit above-branch quadrupedal grasping and climbing. [texte imprimé] / Craig D. Byron . - 2009 . - p. 34-40. Langues : Anglais ( eng) in LabAnimal-Europe > 12/09 (Décembre 2009) . - p. 34-40
Résumé : |
The fine-branch niche is a natural setting found among the slender vines and terminal branches of shrubs and tree canopies. In this study, the authors designed two simulations of this setting for laboratory mice. Their main goal was to model phenotypic plasticity in a small, clawed mammal, in order to better understand the effect of a thin-branch arboreal setting on musculoskeletal growth and behavior of these animals. The authors exposed mice to the smaller climbing setting for limited amounts of time (e.g., 30 min) and used the larger setting to permanently house another group of mice. Mice in both the limited and continuous climbing groups succeeded at quadrupedal climbing among a complex of thin branch segments. This led the authors to postulate that similarly sized pre-primates that lacked the unique features of today's primates could potentially have exploited this niche. The mice housed in the continuous model remained healthy and showed no signs of aggression, leading the authors to suggest that animal care personnel could use similar models as forms of enrichment for laboratory mice. |
Permalink : |
./index.php?lvl=notice_display&id=76462 |
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Exemplaires (1)
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Revue | Revue | Centre de Documentation HELHa Campus Montignies | Réserve | Consultable sur demande auprès des documentalistes Exclu du prêt |
[article]
Titre : |
An automated feeding and behavior monitoring system for rodents. |
Type de document : |
texte imprimé |
Auteurs : |
Elio Furlano |
Année de publication : |
2009 |
Article en page(s) : |
p. 42-47 |
Langues : |
Anglais (eng) |
Résumé : |
To develop pharmaceutical treatments for obesity and diabetes, researchers carry out food intake studies and more in-depth assessments of the feeding behavior in rodents. To facilitate such studies, the authors designed and developed a rodent behavior monitoring system that simultaneously measures food intake, water consumption and motor activity. When tested, their Automated Water Food Activity System (AWFAS) substantially increased throughput for routine rat food intake studies and also improved user ergonomics and safety. The authors describe their system and suggest that others could design similar systems or adapt certain features of the AWFAS to fit existing rodent caging systems. |
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./index.php?lvl=notice_display&id=76463 |
in LabAnimal-Europe > 12/09 (Décembre 2009) . - p. 42-47
[article] An automated feeding and behavior monitoring system for rodents. [texte imprimé] / Elio Furlano . - 2009 . - p. 42-47. Langues : Anglais ( eng) in LabAnimal-Europe > 12/09 (Décembre 2009) . - p. 42-47
Résumé : |
To develop pharmaceutical treatments for obesity and diabetes, researchers carry out food intake studies and more in-depth assessments of the feeding behavior in rodents. To facilitate such studies, the authors designed and developed a rodent behavior monitoring system that simultaneously measures food intake, water consumption and motor activity. When tested, their Automated Water Food Activity System (AWFAS) substantially increased throughput for routine rat food intake studies and also improved user ergonomics and safety. The authors describe their system and suggest that others could design similar systems or adapt certain features of the AWFAS to fit existing rodent caging systems. |
Permalink : |
./index.php?lvl=notice_display&id=76463 |
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Exemplaires (1)
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Revue | Revue | Centre de Documentation HELHa Campus Montignies | Réserve | Consultable sur demande auprès des documentalistes Exclu du prêt |
[article]
Titre : |
The susceptibility of three strains of Chinese minipigs to diet-induced type 2 diabetes mellitus. |
Type de document : |
texte imprimé |
Auteurs : |
Hua Chen |
Année de publication : |
2009 |
Article en page(s) : |
p. 14-24 |
Langues : |
Anglais (eng) |
Résumé : |
Researchers have extensively used animal models to study diabetes mellitus. In this study, the authors determined the susceptibility of three strains of Chinese minipigs to diet-induced type 2 diabetes mellitus. For 8 months, the researchers fed Nongda control minipigs (n=4) a normal diet and fed Bama, Wuzhishan and Nongda minipigs (n=6 per group) a high-sucrose, high-fat diet. They measured the minipigs' body weights, fasting serum glucose concentrations and insulin concentrations each month. Every 2 months, they measured serum triglyceride, cholesterol, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels and carried out intravenous glucose tolerance tests (IVGTTs). The Bama and Wuzhishan minipigs were relatively susceptible to diabetes induced by the high-sucrose, high-fat diet, though susceptibility differed among individual animals in the same strain. On the other hand, Nongda minipigs were relatively resistant to diet-induced diabetes. These results provide a foundation for diabetes-related genetic analyses in minipigs with high and low susceptibility to diet-induced type 2 diabetes. |
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./index.php?lvl=notice_display&id=76466 |
in LabAnimal-Europe > 12/09 (Décembre 2009) . - p. 14-24
[article] The susceptibility of three strains of Chinese minipigs to diet-induced type 2 diabetes mellitus. [texte imprimé] / Hua Chen . - 2009 . - p. 14-24. Langues : Anglais ( eng) in LabAnimal-Europe > 12/09 (Décembre 2009) . - p. 14-24
Résumé : |
Researchers have extensively used animal models to study diabetes mellitus. In this study, the authors determined the susceptibility of three strains of Chinese minipigs to diet-induced type 2 diabetes mellitus. For 8 months, the researchers fed Nongda control minipigs (n=4) a normal diet and fed Bama, Wuzhishan and Nongda minipigs (n=6 per group) a high-sucrose, high-fat diet. They measured the minipigs' body weights, fasting serum glucose concentrations and insulin concentrations each month. Every 2 months, they measured serum triglyceride, cholesterol, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels and carried out intravenous glucose tolerance tests (IVGTTs). The Bama and Wuzhishan minipigs were relatively susceptible to diabetes induced by the high-sucrose, high-fat diet, though susceptibility differed among individual animals in the same strain. On the other hand, Nongda minipigs were relatively resistant to diet-induced diabetes. These results provide a foundation for diabetes-related genetic analyses in minipigs with high and low susceptibility to diet-induced type 2 diabetes. |
Permalink : |
./index.php?lvl=notice_display&id=76466 |
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Exemplaires (1)
|
Revue | Revue | Centre de Documentation HELHa Campus Montignies | Réserve | Consultable sur demande auprès des documentalistes Exclu du prêt |