Dépouillements

Periurethral swelling in a female C3H/HeNCrMTV mouse. / Leanne C. Alworth in LabAnimal-Europe, 6/09 (Juin 2009)

Public ISBD [article]  inLabAnimal-Europe > 6/09 (Juin 2009) . - p. 10-14 Titre : Periurethral swelling in a female C3H/HeNCrMTV mouse. Type de document : texte imprimé Auteurs : Leanne C. Alworth Année de publication : 2009 Article en page(s) : p. 10-14 Langues : Anglais (eng) Permalink : ./index.php?lvl=notice_display&id=76438 [article] Periurethral swelling in a female C3H/HeNCrMTV mouse. [texte imprimé] / Leanne C. Alworth . - 2009 . - p. 10-14. Langues : Anglais (eng) in LabAnimal-Europe > 6/09 (Juin 2009) . - p. 10-14 Permalink : ./index.php?lvl=notice_display&id=76438

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Analysis of environmental sound levels in modern rodent housing rooms / Amanda M. Lauer in LabAnimal-Europe, 6/09 (Juin 2009)

Public ISBD [article]  inLabAnimal-Europe > 6/09 (Juin 2009) . - p. 17-24 Titre : Analysis of environmental sound levels in modern rodent housing rooms Type de document : texte imprimé Auteurs : Amanda M. Lauer Année de publication : 2009 Article en page(s) : p. 17-24 Langues : Anglais (eng) Résumé : Noise in animal housing facilities is an environmental variable that can affect hearing, behavior and physiology in mice. The authors measured sound levels in two rodent housing rooms (room 1 and room 2) during several 24-h periods. Room 1, which was subject to heavy personnel traffic, contained ventilated racks and static cages that housed large numbers of mice. Room 2 was accessed by only a few staff members, contained static cages only and housed fewer mice. In both rooms, background sound levels were usually about 80 dB, and transient noises caused sound levels to temporarily rise 30-40 dB above the baseline level; such peaks occurred frequently during work hours (8:30 AM to 4:30 PM) and infrequently during non-work hours. Noise peaks during work hours in room 1 occurred about two times as often as in room 2 (P = 0.01). Use of changing stations located in the rooms caused background noise to increase by about 10 dB. Loud noise and noise variability were attributed mainly to personnel activity. Attempts to reduce noise should concentrate on controlling sounds produced by in-room activities and experimenter traffic; this may reduce the variability of research outcomes and improve animal welfare. Permalink : ./index.php?lvl=notice_display&id=76439 [article] Analysis of environmental sound levels in modern rodent housing rooms [texte imprimé] / Amanda M. Lauer . - 2009 . - p. 17-24. Langues : Anglais (eng) in LabAnimal-Europe > 6/09 (Juin 2009) . - p. 17-24 Résumé : Noise in animal housing facilities is an environmental variable that can affect hearing, behavior and physiology in mice. The authors measured sound levels in two rodent housing rooms (room 1 and room 2) during several 24-h periods. Room 1, which was subject to heavy personnel traffic, contained ventilated racks and static cages that housed large numbers of mice. Room 2 was accessed by only a few staff members, contained static cages only and housed fewer mice. In both rooms, background sound levels were usually about 80 dB, and transient noises caused sound levels to temporarily rise 30-40 dB above the baseline level; such peaks occurred frequently during work hours (8:30 AM to 4:30 PM) and infrequently during non-work hours. Noise peaks during work hours in room 1 occurred about two times as often as in room 2 (P = 0.01). Use of changing stations located in the rooms caused background noise to increase by about 10 dB. Loud noise and noise variability were attributed mainly to personnel activity. Attempts to reduce noise should concentrate on controlling sounds produced by in-room activities and experimenter traffic; this may reduce the variability of research outcomes and improve animal welfare. Permalink : ./index.php?lvl=notice_display&id=76439

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A serological survey to evaluate contemporary prevalence of viral agents and Mycoplasma pulmonis in laboratory mice and rats in western Europe. / Michael Mähler in LabAnimal-Europe, 6/09 (Juin 2009)

Public ISBD [article]  inLabAnimal-Europe > 6/09 (Juin 2009) . - p. 28-33 Titre : A serological survey to evaluate contemporary prevalence of viral agents and Mycoplasma pulmonis in laboratory mice and rats in western Europe. Type de document : texte imprimé Auteurs : Michael Mähler Année de publication : 2009 Article en page(s) : p. 28-33 Langues : Anglais (eng) Résumé : To evaluate current prevalence rates of 24 viruses and of the bacterium Mycoplasma pulmonis, the authors retrospectively surveyed serological data obtained from laboratory mice and rats housed in more than 100 western European institutions. Serum samples were submitted to the authors' institution for testing between January 2007 and June 2008. The prevalence of an infection was defined as the percentage of tested samples that yielded positive results for a specific agent. In mice, the most commonly detected infectious agents were murine norovirus (prevalence of 31.8%), mouse hepatitis virus (5.5%), mouse rotavirus (1.7%) and parvoviruses (1.0%). In rats, parvoviruses (12.1%) and M. pulmonis (3.6%) were the most prevalent infectious agents. Most rodent parvovirus infections could be attributed to mouse parvovirus in mice and to rat minute virus or to Kilham rat virus in rats. These data suggest the importance of up-to-date animal health monitoring programs and should stimulate the scientific community to further improve the microbiological quality of laboratory rodents. Permalink : ./index.php?lvl=notice_display&id=76440 [article] A serological survey to evaluate contemporary prevalence of viral agents and Mycoplasma pulmonis in laboratory mice and rats in western Europe. [texte imprimé] / Michael Mähler . - 2009 . - p. 28-33. Langues : Anglais (eng) in LabAnimal-Europe > 6/09 (Juin 2009) . - p. 28-33 Résumé : To evaluate current prevalence rates of 24 viruses and of the bacterium Mycoplasma pulmonis, the authors retrospectively surveyed serological data obtained from laboratory mice and rats housed in more than 100 western European institutions. Serum samples were submitted to the authors' institution for testing between January 2007 and June 2008. The prevalence of an infection was defined as the percentage of tested samples that yielded positive results for a specific agent. In mice, the most commonly detected infectious agents were murine norovirus (prevalence of 31.8%), mouse hepatitis virus (5.5%), mouse rotavirus (1.7%) and parvoviruses (1.0%). In rats, parvoviruses (12.1%) and M. pulmonis (3.6%) were the most prevalent infectious agents. Most rodent parvovirus infections could be attributed to mouse parvovirus in mice and to rat minute virus or to Kilham rat virus in rats. These data suggest the importance of up-to-date animal health monitoring programs and should stimulate the scientific community to further improve the microbiological quality of laboratory rodents. Permalink : ./index.php?lvl=notice_display&id=76440

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A critical appraisal of open- and closed-chest models of experimental myocardial ischemia / Sofoklis Mitsos in LabAnimal-Europe, 6/09 (Juin 2009)

Public ISBD [article]  inLabAnimal-Europe > 6/09 (Juin 2009) . - p. 34-47 Titre : A critical appraisal of open- and closed-chest models of experimental myocardial ischemia Type de document : texte imprimé Auteurs : Sofoklis Mitsos Année de publication : 2009 Article en page(s) : p. 34-47 Langues : Anglais (eng) Résumé : Myocardial ischemia is one of the most extensively studied topics in modern cardiovascular research. Early investigators first reported experimental myocardial ischemia (EMI) in 1862. The open-chest (surgical) approach is a well-developed model of EMI that enables researchers to directly access and observe the heart. With this approach, EMI is generally induced by surgical ligation of a coronary artery. A drawback of the open-chest model is the need for major surgery, which can result in local and systemic side effects. Alternative closed-chest models of EMI have been developed; most of these models involve endovascular catheterization with coronary artery embolization or thrombosis. Closed-chest techniques eliminate the need for invasive surgery, and the resultant model is more physiologically similar to clinical myocardial ischemia than is EMI produced by artery ligation. The authors present a review of open- and closed-chest models of EMI and discuss the advantages and disadvantages of each approach. Permalink : ./index.php?lvl=notice_display&id=76441 [article] A critical appraisal of open- and closed-chest models of experimental myocardial ischemia [texte imprimé] / Sofoklis Mitsos . - 2009 . - p. 34-47. Langues : Anglais (eng) in LabAnimal-Europe > 6/09 (Juin 2009) . - p. 34-47 Résumé : Myocardial ischemia is one of the most extensively studied topics in modern cardiovascular research. Early investigators first reported experimental myocardial ischemia (EMI) in 1862. The open-chest (surgical) approach is a well-developed model of EMI that enables researchers to directly access and observe the heart. With this approach, EMI is generally induced by surgical ligation of a coronary artery. A drawback of the open-chest model is the need for major surgery, which can result in local and systemic side effects. Alternative closed-chest models of EMI have been developed; most of these models involve endovascular catheterization with coronary artery embolization or thrombosis. Closed-chest techniques eliminate the need for invasive surgery, and the resultant model is more physiologically similar to clinical myocardial ischemia than is EMI produced by artery ligation. The authors present a review of open- and closed-chest models of EMI and discuss the advantages and disadvantages of each approach. Permalink : ./index.php?lvl=notice_display&id=76441

Exemplaires (1)

Cote	Support	Localisation	Section	Disponibilité
Revue	Revue	Centre de Documentation HELHa Campus Montignies	Réserve	Consultable sur demande auprès des documentalistes Exclu du prêt