[article] 
inAmerican Journal of Occupational Therapy > Vol. 67/2 (mars-avril 2013) . - p. 154-161

Titre :	Recruitment, retention, and blinding in clinical trials
Type de document :	texte imprimé
Auteurs :	Stephen J. PAGE ; Andrew C. PERSCH
Année de publication :	2013
Article en page(s) :	p. 154-161
Langues :	Anglais (eng)
Mots-clés :	Essai thérapeutique  Critère sélection  Malade
Résumé :	The recruitment and retention of participants and the blinding of participants, health care providers, and data collectors present challenges for clinical trial investigators. This article reviews challenges and alternative strategies associated with these three important clinical trial activities. Common recruiting pitfalls, including low sample size, unfriendly study designs, suboptimal testing locations, and untimely recruitment are discussed together with strategies for overcoming these barriers. The use of active controls, technology-supported visit reminders, and up-front scheduling is recommended to prevent attrition and maximize retention of participants. Blinding is conceptualized as the process of concealing research design elements from key players in the research process. Strategies for blinding participants, health care providers, and data collectors are suggested.
Permalink :	./index.php?lvl=notice_display&id=14211

[article] Recruitment, retention, and blinding in clinical trials [texte imprimé] / Stephen J. PAGE ; Andrew C. PERSCH . - 2013 . - p. 154-161.
Langues : Anglais (eng)
in American Journal of Occupational Therapy > Vol. 67/2 (mars-avril 2013) . - p. 154-161

Mots-clés :	Essai thérapeutique  Critère sélection  Malade
Résumé :	The recruitment and retention of participants and the blinding of participants, health care providers, and data collectors present challenges for clinical trial investigators. This article reviews challenges and alternative strategies associated with these three important clinical trial activities. Common recruiting pitfalls, including low sample size, unfriendly study designs, suboptimal testing locations, and untimely recruitment are discussed together with strategies for overcoming these barriers. The use of active controls, technology-supported visit reminders, and up-front scheduling is recommended to prevent attrition and maximize retention of participants. Blinding is conceptualized as the process of concealing research design elements from key players in the research process. Strategies for blinding participants, health care providers, and data collectors are suggested.
Permalink :	./index.php?lvl=notice_display&id=14211