[article] 
inActa Orthopaedica Belgica > Vol. 87/4 (Décembre 2021) . - p. 697-703

Titre :	Should tranexamic acid be used for 3 days after total knee replacement? : a randomized study in 250 patients
Type de document :	texte imprimé
Auteurs :	Nilen Shah, Auteur ; Vatsal Khetan, Auteur ; Hari Sivanadan
Année de publication :	2021
Article en page(s) :	p. 697-703
Note générale :	https://doi.org/10.52628/87.4.14
Langues :	Anglais (eng)
Mots-clés :	Tranexamic acid  total knee replacement  routes  duration
Résumé :	The aim is to study whether a 3 day course of Tranexamic acid (TXA) is more effective in reducing blood loss following a TKR than a 1 day course. 250 patients were prospectively randomised into Group A (n=138; Perioperative and additional oral TXA for two days) and Group B (n=112; only perioperative TXA). Total Blood loss was calculated by the Haemoglobin (Hb) loss method at 4 days and compared in both groups using Mann Whitney test. The mean peri- operative blood loss in group A was 631.69 ± 264.99 ml as compared to 685.55 ± 239.033 ml in group B (p=0.0434). Use of TXA for 3 days following a TKR can be more effective in reducing blood loss.
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[article] Should tranexamic acid be used for 3 days after total knee replacement? : a randomized study in 250 patients [texte imprimé] / Nilen Shah, Auteur ; Vatsal Khetan, Auteur ; Hari Sivanadan . - 2021 . - p. 697-703.
https://doi.org/10.52628/87.4.14
Langues : Anglais (eng)
in Acta Orthopaedica Belgica > Vol. 87/4 (Décembre 2021) . - p. 697-703

Mots-clés :	Tranexamic acid  total knee replacement  routes  duration
Résumé :	The aim is to study whether a 3 day course of Tranexamic acid (TXA) is more effective in reducing blood loss following a TKR than a 1 day course. 250 patients were prospectively randomised into Group A (n=138; Perioperative and additional oral TXA for two days) and Group B (n=112; only perioperative TXA). Total Blood loss was calculated by the Haemoglobin (Hb) loss method at 4 days and compared in both groups using Mann Whitney test. The mean peri- operative blood loss in group A was 631.69 ± 264.99 ml as compared to 685.55 ± 239.033 ml in group B (p=0.0434). Use of TXA for 3 days following a TKR can be more effective in reducing blood loss.
Permalink :	./index.php?lvl=notice_display&id=102049